Yellow Fever

Emily H. Davis, Alan D.T. Barrett

Research output: Chapter in Book/Report/Conference proceedingChapter


Yellow fever (YF) is a disease caused by yellow fever virus (YFV), a mosquito-borne flavivirus found in Sub-Saharan Africa and tropical South America. The virus exists in a transmission cycle involving tree-hole breeding mosquitoes and non-human primates with the exact species of mosquito and primate varying by geographic location. The disease YF gets its name from virus-infection of the liver resulting in liver dysfunction such that the skin of those infected turns yellow. There are no treatments for YF other than supportive care but there is a very effective live attenuated vaccine, termed 17D. Despite the availability of a vaccine there are still over 100,000 severe YF cases and over 50,000 deaths each year.

Original languageEnglish (US)
Title of host publicationManson's Tropical Diseases, Fourth Edition
Number of pages5
ISBN (Electronic)9780702079597
ISBN (Print)9780702079627
StatePublished - Jan 1 2023


  • flavivirus
  • mosquito
  • vaccine
  • yellow fever

ASJC Scopus subject areas

  • General Medicine


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