Yellow Fever

Emily H. Davis; Alan D.T. Barrett

doi:10.1016/B978-0-7020-7959-7.00019-1

Yellow Fever

Emily H. Davis, Alan D.T. Barrett

Pathology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Yellow fever (YF) is a disease caused by yellow fever virus (YFV), a mosquito-borne flavivirus found in Sub-Saharan Africa and tropical South America. The virus exists in a transmission cycle involving tree-hole breeding mosquitoes and non-human primates with the exact species of mosquito and primate varying by geographic location. The disease YF gets its name from virus-infection of the liver resulting in liver dysfunction such that the skin of those infected turns yellow. There are no treatments for YF other than supportive care but there is a very effective live attenuated vaccine, termed 17D. Despite the availability of a vaccine there are still over 100,000 severe YF cases and over 50,000 deaths each year.

Original language	English (US)
Title of host publication	Manson's Tropical Diseases, Fourth Edition
Publisher	Elsevier
Pages	167-171
Number of pages	5
ISBN (Electronic)	9780702079597
ISBN (Print)	9780702079627
DOIs	https://doi.org/10.1016/B978-0-7020-7959-7.00019-1
State	Published - Jan 1 2023

Keywords

flavivirus
mosquito
vaccine
yellow fever

ASJC Scopus subject areas

General Medicine

Access to Document

10.1016/B978-0-7020-7959-7.00019-1

Cite this

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AB - Yellow fever (YF) is a disease caused by yellow fever virus (YFV), a mosquito-borne flavivirus found in Sub-Saharan Africa and tropical South America. The virus exists in a transmission cycle involving tree-hole breeding mosquitoes and non-human primates with the exact species of mosquito and primate varying by geographic location. The disease YF gets its name from virus-infection of the liver resulting in liver dysfunction such that the skin of those infected turns yellow. There are no treatments for YF other than supportive care but there is a very effective live attenuated vaccine, termed 17D. Despite the availability of a vaccine there are still over 100,000 severe YF cases and over 50,000 deaths each year.

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Yellow Fever

Abstract

Keywords

ASJC Scopus subject areas

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