What, How, and How Much Should Patients with Burns be Fed?

Felicia N. Williams; Ludwik K. Branski; Marc G. Jeschke; David N. Herndon

doi:10.1016/j.suc.2011.03.002

What, How, and How Much Should Patients with Burns be Fed?

Felicia N. Williams, Ludwik K. Branski, Marc G. Jeschke, David N. Herndon

Surgery

Research output: Contribution to journal › Review article › peer-review

44 Scopus citations

Abstract

The hypermetabolic response to severe burn injury is characterized by hyperdynamic circulation and profound metabolic, physiologic, catabolic, and immune system derangements. Failure to satisfy overwhelming energy and protein requirements after, and during, severe burn injury results in multiorgan dysfunction, increased susceptibility to infection, and death. Attenuation of the hypermetabolic response by various pharmacologic modalities is emerging as an essential component of the management of patients with severe burn injury. This review focuses on the more recent advances in therapeutic strategies to attenuate the hypermetabolic response and its postburn-associated insulin resistance.

Original language	English (US)
Pages (from-to)	609-629
Number of pages	21
Journal	Surgical Clinics of North America
Volume	91
Issue number	3
DOIs	https://doi.org/10.1016/j.suc.2011.03.002
State	Published - Jun 2011

Keywords

Burn injury
Hypermetabolic response
Nutrition
Trauma

ASJC Scopus subject areas

Surgery

Access to Document

10.1016/j.suc.2011.03.002

Cite this

@article{9049157e14f149e1b1b67e7e787aba38,

title = "What, How, and How Much Should Patients with Burns be Fed?",

abstract = "The hypermetabolic response to severe burn injury is characterized by hyperdynamic circulation and profound metabolic, physiologic, catabolic, and immune system derangements. Failure to satisfy overwhelming energy and protein requirements after, and during, severe burn injury results in multiorgan dysfunction, increased susceptibility to infection, and death. Attenuation of the hypermetabolic response by various pharmacologic modalities is emerging as an essential component of the management of patients with severe burn injury. This review focuses on the more recent advances in therapeutic strategies to attenuate the hypermetabolic response and its postburn-associated insulin resistance.",

keywords = "Burn injury, Hypermetabolic response, Nutrition, Trauma",

author = "Williams, {Felicia N.} and Branski, {Ludwik K.} and Jeschke, {Marc G.} and Herndon, {David N.}",

note = "Funding Information: Supported by SHC Grant # 8660 , SHC Grant # 8490 , SHC Grant # 8640 , SHC Grant # 8760 , SHC Grant # 9145 , NIH Training Grant # 2T32GM0825611 , NIH Center Grant # 1P50GM60338-01 , NIH Grant # 5RO1GM56687-03 , NIH R01-GM56687 , NIH Grant # R01-HD049471 , NIDDR H133A020102 , NIDDR H133A70019 , NIGMS U54/GM62119 , American Surgical Association. ",

year = "2011",

month = jun,

doi = "10.1016/j.suc.2011.03.002",

language = "English (US)",

volume = "91",

pages = "609--629",

journal = "Surgical Clinics of North America",

issn = "0039-6109",