West Nile virus methyltransferase catalyzes two methylations of the viral RNA cap through a substrate-repositioning mechanism

Biochemistry, Genetics and Molecular Biology

• Adenosine 12%
• Amino Acids 12%
• Binding Site 37%
• Biochemical Analysis 12%
• Crystal Structure 12%
• Flavivirus 50%
• Guanine 12%
• Methionine 62%
• Methylation 100%
• Methyltransferase 100%
• Molecule 12%
• O-Methylation 25%
• Position 12%
• RNA 100%
• RNA Binding 12%
• Virus Replication 12%
• West Nile Virus 100%

INIS

• adenosine 11%
• amino acids 11%
• crystal structure 11%
• guanine 11%
• methionine 55%
• methyl transferases 100%
• methylation 100%
• molecules 11%
• rna 100%
• substrates 100%
• therapy 11%
• viruses 100%

Keyphrases

• Cap Hypermethylation 60%
• Replication Inhibitor 20%