Viral load and acute otitis media development after human metapneumovirus upper respiratory tract infection

Johanna Nokso-Koivisto; Richard B. Pyles; Aaron L. Miller; Janak A. Patel; Michael Loeffelholz; Tasnee Chonmaitree

doi:10.1097/INF.0b013e3182539d92

Viral load and acute otitis media development after human metapneumovirus upper respiratory tract infection

Johanna Nokso-Koivisto, Richard B. Pyles, Aaron L. Miller, Janak A. Patel, Michael Loeffelholz, Tasnee Chonmaitree

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

The role of human metapneumovirus (hMPV) in acute otitis media complicating upper respiratory tract infection (URI) was studied. Nasopharyngeal specimens from 700 URI episodes in 200 children were evaluated; 47 (7%) were positive for hMPV, 25 (3.6%) with hMPV as the only virus. Overall, 24% of URI episodes with hMPV only were complicated by acute otitis media, which was the lowest rate compared with other respiratory viruses. hMPV viral load was significantly higher in children with fever, but there was no difference in viral load in children with hMPV-positive URI with or without acute otitis media complication.

Original language	English (US)
Pages (from-to)	763-766
Number of pages	4
Journal	Pediatric Infectious Disease Journal
Volume	31
Issue number	7
DOIs	https://doi.org/10.1097/INF.0b013e3182539d92
State	Published - Jul 2012

Keywords

Acute otitis media
Human metapneumovirus
Upper respiratory tract infection
Viral load

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Microbiology (medical)
Infectious Diseases

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10.1097/INF.0b013e3182539d92

Cite this

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title = "Viral load and acute otitis media development after human metapneumovirus upper respiratory tract infection",

abstract = "The role of human metapneumovirus (hMPV) in acute otitis media complicating upper respiratory tract infection (URI) was studied. Nasopharyngeal specimens from 700 URI episodes in 200 children were evaluated; 47 (7%) were positive for hMPV, 25 (3.6%) with hMPV as the only virus. Overall, 24% of URI episodes with hMPV only were complicated by acute otitis media, which was the lowest rate compared with other respiratory viruses. hMPV viral load was significantly higher in children with fever, but there was no difference in viral load in children with hMPV-positive URI with or without acute otitis media complication.",

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AU - Nokso-Koivisto, Johanna

AU - Pyles, Richard B.

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AU - Patel, Janak A.

AU - Loeffelholz, Michael

AU - Chonmaitree, Tasnee

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Viral load and acute otitis media development after human metapneumovirus upper respiratory tract infection

Abstract

Keywords

ASJC Scopus subject areas

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