TY - JOUR
T1 - Viable Cryopreserved Aortic Homograft for Aortic Valve Endocarditis and Annular Abscesses
AU - Zwischenberger, Joseph B.
AU - Shalaby, Tarek Zaghloul
AU - Conti, Vincent R.
N1 - Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 1989
Y1 - 1989
N2 - Six consecutive patients with active aortic valve endocarditis, including 2 with extensive subannular aortic root abscess, were successfully treated with viable cryopreserved homograft aortic valve replacement. Two patients required extensive aortic root reconstruction with an appropriately trimmed aortic homograft to cover large abscess cavities. All patients showed resolution of infection with no perioperative mortality or clinically significant morbidity. Three patients had a minor degree of aortic insufficiency on postoperative echo-Doppler study. On follow-up at 6 to 48 months, all patients were in New York Heart Association functional class I. The resistance of the unstented homograft to infection makes it an attractive choice for patients requiring aortic valve replacement for active endocarditis. The results of surgical intervention in patients with extensive aortic root involvement may be further improved by the flexibility afforded by the homograft to be “custom-fit” to the abnormal aortic root and the ability to achieve secure valve fixation without use of prosthetic material.
AB - Six consecutive patients with active aortic valve endocarditis, including 2 with extensive subannular aortic root abscess, were successfully treated with viable cryopreserved homograft aortic valve replacement. Two patients required extensive aortic root reconstruction with an appropriately trimmed aortic homograft to cover large abscess cavities. All patients showed resolution of infection with no perioperative mortality or clinically significant morbidity. Three patients had a minor degree of aortic insufficiency on postoperative echo-Doppler study. On follow-up at 6 to 48 months, all patients were in New York Heart Association functional class I. The resistance of the unstented homograft to infection makes it an attractive choice for patients requiring aortic valve replacement for active endocarditis. The results of surgical intervention in patients with extensive aortic root involvement may be further improved by the flexibility afforded by the homograft to be “custom-fit” to the abnormal aortic root and the ability to achieve secure valve fixation without use of prosthetic material.
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U2 - 10.1016/S0003-4975(10)62858-5
DO - 10.1016/S0003-4975(10)62858-5
M3 - Article
C2 - 2774720
AN - SCOPUS:0024414719
SN - 0003-4975
VL - 48
SP - 365
EP - 370
JO - Annals of Thoracic Surgery
JF - Annals of Thoracic Surgery
IS - 3
ER -