Venezuelan Equine Encephalitis Virus Activity in the Gulf Coast Region of Mexico, 2003-2010

A. Paige Adams, Roberto Navarro-Lopez, Francisco J. Ramirez-Aguilar, Irene Lopez-Gonzalez, Grace Leal, Jose M. Flores-Mayorga, Amelia P.A. Travassos da Rosa, Kali D. Saxton-Shaw, Amber J. Singh, Erin M. Borland, Ann M. Powers, Robert B. Tesh, Scott C. Weaver, Jose G. Estrada-Franco

Research output: Contribution to journalArticlepeer-review

26 Scopus citations


Venezuelan equine encephalitis virus (VEEV) has been the causative agent for sporadic epidemics and equine epizootics throughout the Americas since the 1930s. In 1969, an outbreak of Venezuelan equine encephalitis (VEE) spread rapidly from Guatemala and through the Gulf Coast region of Mexico, reaching Texas in 1971. Since this outbreak, there have been very few studies to determine the northward extent of endemic VEEV in this region. This study reports the findings of serologic surveillance in the Gulf Coast region of Mexico from 2003-2010. Phylogenetic analysis was also performed on viral isolates from this region to determine whether there have been substantial genetic changes in VEEV since the 1960s. Based on the findings of this study, the Gulf Coast lineage of subtype IE VEEV continues to actively circulate in this region of Mexico and appears to be responsible for infection of humans and animals throughout this region, including the northern State of Tamaulipas, which borders Texas.

Original languageEnglish (US)
Article numbere1875
JournalPLoS neglected tropical diseases
Issue number11
StatePublished - Nov 2012

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Infectious Diseases


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