Use of patient navigators to increase HPV vaccination rates in a pediatric clinical population

Abbey B. Berenson, Jacqueline M. Hirth, Yong Fang Kuo, Jonathan M. Starkey, Richard E. Rupp

Research output: Contribution to journalArticlepeer-review


A patient navigator (PN) program was implemented in pediatric clinics to increase uptake of the human papillomavirus (HPV) vaccine. The purpose of this study is to examine the impact of this program. All visits between April 1, 2013 and December 31, 2017 for 9–17 year old patients at 3 program and 5 non-program clinics were examined using electronic medical records. These dates included patient visits before and after program initiation (February 1, 2015). Visits including 1 dose of the HPV vaccine were assessed as a proportion of total visits for each month. Multivariable binary logistic regression was used to examine the odds of HPV vaccination across time, between program and non-program clinics, and age group. A total of 128,051 visits by 21,395 patients were examined. HPV vaccines were administered during 12,742 visits (10.0%). Odds of HPV vaccination during visits by 13–17 year olds was greater than during visits by 9–12 year olds in the pre-intervention period (odds ratio [OR]: 1.12, 95% confidence interval [CI]: 1.04–1.19). However, this association changed during the intervention period, with odds of HPV vaccination among visits by 13–17 year olds lower compared to visits by 9–12 year olds (OR: 0.78, 95% CI: 0.75–0.82). The odds of HPV vaccination were elevated among 9–12 year olds in program clinics as compared to 2014, the year before the program was implemented. Having on-site PNs can increase the frequency of HPV vaccination in pediatric clinics, particularly among patients 9–12 years of age.

Original languageEnglish (US)
Article number101194
JournalPreventive Medicine Reports
StatePublished - Dec 2020


  • Cancer prevention
  • Clinical intervention
  • HPV vaccination
  • Patient navigators
  • Population Health

ASJC Scopus subject areas

  • Health Informatics
  • Public Health, Environmental and Occupational Health


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