Ultrastructural characterization of a new member of the Rhabdovirus group-Klamath virus

Frederick A. Murphy; Harald N. Johnson; Alyne K. Hareison; Robert E. Shope

doi:10.1007/BF01241455

Ultrastructural characterization of a new member of the Rhabdovirus group-Klamath virus

Frederick A. Murphy, Harald N. Johnson, Alyne K. Hareison, Robert E. Shope

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Klamath virus was observed by negative contrast and thin section electron microscopy. Bullet-shaped particles in infected cell cultures had mean dimensions of 167×80 nm and were typical of members of the Rhabdovirus group. In infected mouse brain, virus particles budded from intracytoplasmic membranes in association with a prominent matrix. Although the virus is serologically unrelated to any of the known Rhabdoviruses of animals, this intracytoplasmic accumulation of virus particles and matrix with little frank cytopathology, most closely resembles in vivo rabies virus infection.

Original language	English (US)
Pages (from-to)	323-331
Number of pages	9
Journal	Archiv für die gesamte Virusforschung
Volume	37
Issue number	4
DOIs	https://doi.org/10.1007/BF01241455
State	Published - Dec 1972
Externally published	Yes

ASJC Scopus subject areas

Applied Microbiology and Biotechnology
Genetics

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title = "Ultrastructural characterization of a new member of the Rhabdovirus group-Klamath virus",

abstract = "Klamath virus was observed by negative contrast and thin section electron microscopy. Bullet-shaped particles in infected cell cultures had mean dimensions of 167×80 nm and were typical of members of the Rhabdovirus group. In infected mouse brain, virus particles budded from intracytoplasmic membranes in association with a prominent matrix. Although the virus is serologically unrelated to any of the known Rhabdoviruses of animals, this intracytoplasmic accumulation of virus particles and matrix with little frank cytopathology, most closely resembles in vivo rabies virus infection.",

author = "Murphy, {Frederick A.} and Johnson, {Harald N.} and Hareison, {Alyne K.} and Shope, {Robert E.}",

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AU - Murphy, Frederick A.

AU - Johnson, Harald N.

AU - Hareison, Alyne K.

AU - Shope, Robert E.

PY - 1972/12

Y1 - 1972/12

N2 - Klamath virus was observed by negative contrast and thin section electron microscopy. Bullet-shaped particles in infected cell cultures had mean dimensions of 167×80 nm and were typical of members of the Rhabdovirus group. In infected mouse brain, virus particles budded from intracytoplasmic membranes in association with a prominent matrix. Although the virus is serologically unrelated to any of the known Rhabdoviruses of animals, this intracytoplasmic accumulation of virus particles and matrix with little frank cytopathology, most closely resembles in vivo rabies virus infection.

AB - Klamath virus was observed by negative contrast and thin section electron microscopy. Bullet-shaped particles in infected cell cultures had mean dimensions of 167×80 nm and were typical of members of the Rhabdovirus group. In infected mouse brain, virus particles budded from intracytoplasmic membranes in association with a prominent matrix. Although the virus is serologically unrelated to any of the known Rhabdoviruses of animals, this intracytoplasmic accumulation of virus particles and matrix with little frank cytopathology, most closely resembles in vivo rabies virus infection.

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Ultrastructural characterization of a new member of the Rhabdovirus group-Klamath virus

Abstract

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