Triple hybrids of steroids, spiroketals, and oligopeptides as new biomolecular chimeras

Abhisek Banerjee; Eduard Sergienko; Stefan Vasile; Vineet Gupta; Kristiina Vuori; Peter Wipf

doi:10.1021/ol802247m

Triple hybrids of steroids, spiroketals, and oligopeptides as new biomolecular chimeras

Abhisek Banerjee, Eduard Sergienko, Stefan Vasile, Vineet Gupta, Kristiina Vuori, Peter Wipf

Research output: Contribution to journal › Article › peer-review

Abstract

An oxidative enol ether rearrangement was the key methodology in the construction of steroid-spiroketal-RGD peptides. Biological studies demonstrated potent integrin CD11b/CD18 antagonistic effects.

Original language	English (US)
Pages (from-to)	65-68
Number of pages	4
Journal	Organic Letters
Volume	11
Issue number	1
DOIs	https://doi.org/10.1021/ol802247m
State	Published - Jan 1 2009
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1021/ol802247m

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title = "Triple hybrids of steroids, spiroketals, and oligopeptides as new biomolecular chimeras",

abstract = "An oxidative enol ether rearrangement was the key methodology in the construction of steroid-spiroketal-RGD peptides. Biological studies demonstrated potent integrin CD11b/CD18 antagonistic effects.",

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year = "2009",

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AU - Banerjee, Abhisek

AU - Sergienko, Eduard

AU - Vasile, Stefan

AU - Gupta, Vineet

AU - Vuori, Kristiina

AU - Wipf, Peter

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Triple hybrids of steroids, spiroketals, and oligopeptides as new biomolecular chimeras

Abstract

ASJC Scopus subject areas

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