Transdermal fentanyl improves management of postoperative hemorrhoidectomy pain

Michael Kilbride, Myron Morse, Anthony Senagore

Research output: Contribution to journalArticlepeer-review

48 Scopus citations


PURPOSE: Outpatient postoperative hemorrhoidectomy pain remains a difficult problem. The purpose of this study is to evaluate the use of transdermal fentanyl for analgesia following hemorrhoidectomy. METHODS: Patients were prospectively randomized in a double-blind fashion to one of two groups, placebo or transdermal fentanyl. Forty-two patients were eligible for the study (placebo, 21; fentanyl, 17; 4 were excluded). A visual analog scale was used to evaluate postoperative pain (0 = no pain; 10 = worst pain). RESULTS: Fewer patients in the fentanyl group (10/17) required postoperative parental narcotics than the placebo group (21/21) (P<0.05 Fisher's exact test). The amount of narcotics consumed postoperatively was significantly less in the fentanyl group (97.05 mg of meperidine ± 23.27) than in the placebo group (236.19 ± 30.46) (P<.05 Student'st-tesf). Pain scores in the fentanyl group were significantly lower (less pain) than in the placebo group (P<0.05 Kruskal-Wallis). CONCLUSION: Results indicate that use of transdermal fentanyl provides an effective analgesic alternative that improves the transition to noninvasive outpatient pain management in the hemorrhoidectomy patient.

Original languageEnglish (US)
Pages (from-to)1070-1072
Number of pages3
JournalDiseases of the Colon & Rectum
Issue number11
StatePublished - Nov 1994
Externally publishedYes


  • Hemorrhoidectomy
  • Pain
  • Postoperative
  • Transdermal fentanyl

ASJC Scopus subject areas

  • Gastroenterology


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