The VP35 and VP40 proteins of filoviruses. Homology between Marburg and Ebola viruses

A. A. Bukreyev; V. E. Volchkov; V. M. Blinov; S. V. Netesov

doi:10.1016/0014-5793(93)81107-B

The VP35 and VP40 proteins of filoviruses. Homology between Marburg and Ebola viruses

A. A. Bukreyev, V. E. Volchkov, V. M. Blinov, S. V. Netesov

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Abstract

The fragments of genomic RNA sequences of Marburg (MBG) and Ebola (EBO) viruses are reported. These fragments were found to encode the VP35 and VP40 proteins. The canonic sequences were revealed before and after each open reading frame. It is suggested that these sequences are mRNA extremities and at the same time the regulatory elements for mRNA transcription. Homology between the MBG and EBO proteins was discovered.

Original language	English (US)
Pages (from-to)	41-46
Number of pages	6
Journal	FEBS Letters
Volume	322
Issue number	1
DOIs	https://doi.org/10.1016/0014-5793(93)81107-B
State	Published - May 3 1993
Externally published	Yes

Keywords

Amino acid sequence
Ebola virus
Filoviridae
Marburg virus
Nucleotide sequence

ASJC Scopus subject areas

Biophysics
Structural Biology
Biochemistry
Molecular Biology
Genetics
Cell Biology

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10.1016/0014-5793(93)81107-B

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AU - Bukreyev, A. A.

AU - Volchkov, V. E.

AU - Blinov, V. M.

AU - Netesov, S. V.

PY - 1993/5/3

Y1 - 1993/5/3

N2 - The fragments of genomic RNA sequences of Marburg (MBG) and Ebola (EBO) viruses are reported. These fragments were found to encode the VP35 and VP40 proteins. The canonic sequences were revealed before and after each open reading frame. It is suggested that these sequences are mRNA extremities and at the same time the regulatory elements for mRNA transcription. Homology between the MBG and EBO proteins was discovered.

AB - The fragments of genomic RNA sequences of Marburg (MBG) and Ebola (EBO) viruses are reported. These fragments were found to encode the VP35 and VP40 proteins. The canonic sequences were revealed before and after each open reading frame. It is suggested that these sequences are mRNA extremities and at the same time the regulatory elements for mRNA transcription. Homology between the MBG and EBO proteins was discovered.

KW - Amino acid sequence

KW - Ebola virus

KW - Filoviridae

KW - Marburg virus

KW - Nucleotide sequence

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The VP35 and VP40 proteins of filoviruses. Homology between Marburg and Ebola viruses

Abstract

Keywords

ASJC Scopus subject areas

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