The Role of Skin Substitutes in Acute Burn and Reconstructive Burn Surgery: An Updated Comprehensive Review

Alen Palackic; Robert P. Duggan; Matthew S. Campbell; Elliot Walters; Ludwik K. Branski; Amina El Ayadi; Steven E. Wolf

doi:10.1055/s-0042-1743455

The Role of Skin Substitutes in Acute Burn and Reconstructive Burn Surgery: An Updated Comprehensive Review

Alen Palackic, Robert P. Duggan, Matthew S. Campbell, Elliot Walters, Ludwik K. Branski, Amina El Ayadi, Steven E. Wolf

Surgery

Research output: Contribution to journal › Review article › peer-review

Abstract

Burns disrupt the protective skin barrier with consequent loss of cutaneous temperature regulation, infection prevention, evaporative losses, and other vital functions. Chronically, burns lead to scarring, contractures, pain, and impaired psychosocial well-being. Several skin substitutes are available and replace the skin and partially restore functional outcomes and improve cosmesis. We performed a literature review to update readers on biologic and synthetic skin substitutes to date applied in acute and reconstructive burn surgery. Improvement has been rapid in the development of skin substitutes in the last decade; however, no available skin substitute fulfills criteria as a perfect replacement for damaged skin.

Original language	English (US)
Pages (from-to)	33-42
Number of pages	10
Journal	Seminars in Plastic Surgery
Volume	36
Issue number	1
DOIs	https://doi.org/10.1055/s-0042-1743455
State	Published - Feb 2022

Keywords

biologics
burns
epithelization
skin
synthetic dressing
total body surface area

ASJC Scopus subject areas

Surgery

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10.1055/s-0042-1743455

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abstract = "Burns disrupt the protective skin barrier with consequent loss of cutaneous temperature regulation, infection prevention, evaporative losses, and other vital functions. Chronically, burns lead to scarring, contractures, pain, and impaired psychosocial well-being. Several skin substitutes are available and replace the skin and partially restore functional outcomes and improve cosmesis. We performed a literature review to update readers on biologic and synthetic skin substitutes to date applied in acute and reconstructive burn surgery. Improvement has been rapid in the development of skin substitutes in the last decade; however, no available skin substitute fulfills criteria as a perfect replacement for damaged skin.",

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AU - Walters, Elliot

AU - Branski, Ludwik K.

AU - Ayadi, Amina El

AU - Wolf, Steven E.

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AB - Burns disrupt the protective skin barrier with consequent loss of cutaneous temperature regulation, infection prevention, evaporative losses, and other vital functions. Chronically, burns lead to scarring, contractures, pain, and impaired psychosocial well-being. Several skin substitutes are available and replace the skin and partially restore functional outcomes and improve cosmesis. We performed a literature review to update readers on biologic and synthetic skin substitutes to date applied in acute and reconstructive burn surgery. Improvement has been rapid in the development of skin substitutes in the last decade; however, no available skin substitute fulfills criteria as a perfect replacement for damaged skin.

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KW - synthetic dressing

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The Role of Skin Substitutes in Acute Burn and Reconstructive Burn Surgery: An Updated Comprehensive Review

Abstract

Keywords

ASJC Scopus subject areas

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