TY - JOUR
T1 - The role of immune reconstitution inflammatory syndrome in AIDS-related Cryptococcus neoformans disease in the era of highly active antiretroviral therapy
AU - Shelburne, Samuel A.
AU - Darcourt, Jorge
AU - White, A. Clinton
AU - Greenberg, Stephen B.
AU - Hamill, Richard J.
AU - Atmar, Robert L.
AU - Visnegarwala, Fehmida
N1 - Funding Information:
We thank Dr. Thomas Giordano and Dr. Robert Lasky for assistance with statistical analysis. Financial support. Bristol-Myers Squibb (HIV fellowship grant to S.A.S.) and the National Institute of Allergy and Infectious Diseases (fellowship grant T32-AI055413 to S.A.S.). Potential conflicts of interest. All authors: no conflicts.
PY - 2005/4/1
Y1 - 2005/4/1
N2 - This study of human immunodeficiency virus (HIV)-infected patients coinfected with Cryptococcus neoformans found that 30% of patients who initiated highly active antiretroviral therapy developed immune reconstitution inflammatory syndrome (IRIS). Patients with C. neoformans-related IRIS had higher cerebrospinal fluid opening pressures, glucose levels, and white blood cell counts, compared with patients with typical HIV-associated C. neoformans meningitis.
AB - This study of human immunodeficiency virus (HIV)-infected patients coinfected with Cryptococcus neoformans found that 30% of patients who initiated highly active antiretroviral therapy developed immune reconstitution inflammatory syndrome (IRIS). Patients with C. neoformans-related IRIS had higher cerebrospinal fluid opening pressures, glucose levels, and white blood cell counts, compared with patients with typical HIV-associated C. neoformans meningitis.
UR - http://www.scopus.com/inward/record.url?scp=15744394140&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=15744394140&partnerID=8YFLogxK
U2 - 10.1086/428618
DO - 10.1086/428618
M3 - Article
C2 - 15825000
AN - SCOPUS:15744394140
SN - 1058-4838
VL - 40
SP - 1049
EP - 1052
JO - Clinical Infectious Diseases
JF - Clinical Infectious Diseases
IS - 7
ER -