The renin-angiotensin system in the pathogenesis of intracranial aneurysms and its complications

Christoph J. Griessenauer, Joel Raborn, R. Shane Tubbs, Martim Mortazavi, Mohammadali M. Shoja

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

"In recent years, the pathophysiology of intracranial (cerebral) aneurysms has been explored by several studies and multiple factors involved in the formation and rupture of intracranial aneurysms have been identified. Currently, researches indicate that the reninangiotensin system (RAS) is one of the many factors potentially involved in the pathogenesis of intracranial aneurysms. This chapter discusses the pathogenesis of intracranial aneurysms, the nature and pathophysiology of the RAS, and how the RAS, specifically the brain RAS, plays a role in the pathogenesis of intracranial aneurysms."

Original languageEnglish (US)
Title of host publicationRenin-Angiotensin System
Subtitle of host publicationPhysiology, Role in Disease and Health Implications
PublisherNova Science Publishers, Inc.
Pages199-208
Number of pages10
ISBN (Print)9781624177880
StatePublished - Apr 2013
Externally publishedYes

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology

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