The National Depressive and Manic-depressive Association (DMDA) survey of bipolar members

Jennifer D. Lish, Susan Dime-Meenan, Peter C. Whybrow, R. Arlen Price, Robert M.A. Hirschfeld

Research output: Contribution to journalArticlepeer-review

730 Scopus citations


Members of the National Depressive and Manic-Depressive Association who have bipolar disorder were surveyed. 59% of respondents had their first symptoms during childhood or adolence. Long delays between symptom onset, treatment-seeking, and receipt of a bipolar diagnosis were common. 45% of respondents currently experience frequent recurrences. Child/adolescent onset was associated with a positive family history, depressive or mixed initial symptoms, and frequent recurrence, with predominantly depressive symptoms. Frequent recurrences were associated with depressive or mixed initial symptoms and depressive episodes, but not with medication non-compliance. Both child/adolescent onset and frequent recurrence were associated with increased social morbidity, which was diminished by effective treatment. Respondents with frequent recurrences were less likely to be treated with mood-stabilizers, more likely to be treated with anti-depressants, or anxiolytics, and more likely to report past anxiety symptoms and diagnoses. 13% of respondents had no medical insurance, and 15% had failed to take medicine for financial reasons. The treatment of bipolar illness could be enhanced by (a) public health efforts to promote early diagnosis and treatment; (b) ensuring adequate trials of mood-stabilizers for patients with frequent recurrences; (c) further research on bipolar disorder with prominent anxiety symptoms; and (c) improved access to mental health care.

Original languageEnglish (US)
Pages (from-to)281-294
Number of pages14
JournalJournal of Affective Disorders
Issue number4
StatePublished - Aug 1994
Externally publishedYes


  • Age of onset
  • Bipolar disorder
  • Course of illness
  • Quality of life
  • Social morbidity
  • Treatment

ASJC Scopus subject areas

  • Clinical Psychology
  • Psychiatry and Mental health


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