The identification of experimentally induced appendicitis using in vitro nuclear magnetic resonance

Danny O. Jacobs; John R. Clarke; R. G. Settle; A. K. Sachdeva; James E. Wheeler; Scott O. Trerotola; Gerald L. Wolf; John L. Rombeau

doi:10.1016/0022-4804(85)90156-8

The identification of experimentally induced appendicitis using in vitro nuclear magnetic resonance

Danny O. Jacobs, John R. Clarke, R. G. Settle, A. K. Sachdeva, James E. Wheeler, Scott O. Trerotola, Gerald L. Wolf, John L. Rombeau

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Appendicitis was induced in six New Zealand white rabbits. The appendices from these animals had significantly higher spin-lattice relaxation times, T1, as determined in vitro by nuclear magnetic resonance (NMR) (10 controls vs 6 experimentals, 413 ± 23 vs 455 ± 41, X ± SD, P < (0.02). T1 correlated significantly with the water content of the appendiceal tissue (P < 0.001). These findings suggest that in vivo NMR imaging techniques weighted on T1 might be able to identify human appendicitis noninvasively by detecting localized edema.

Original language	English (US)
Pages (from-to)	16-24
Number of pages	9
Journal	Journal of Surgical Research
Volume	39
Issue number	1
DOIs	https://doi.org/10.1016/0022-4804(85)90156-8
State	Published - Jul 1985
Externally published	Yes

ASJC Scopus subject areas

Surgery

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title = "The identification of experimentally induced appendicitis using in vitro nuclear magnetic resonance",

abstract = "Appendicitis was induced in six New Zealand white rabbits. The appendices from these animals had significantly higher spin-lattice relaxation times, T1, as determined in vitro by nuclear magnetic resonance (NMR) (10 controls vs 6 experimentals, 413 ± 23 vs 455 ± 41, X ± SD, P < (0.02). T1 correlated significantly with the water content of the appendiceal tissue (P < 0.001). These findings suggest that in vivo NMR imaging techniques weighted on T1 might be able to identify human appendicitis noninvasively by detecting localized edema.",

author = "Jacobs, {Danny O.} and Clarke, {John R.} and Settle, {R. G.} and Sachdeva, {A. K.} and Wheeler, {James E.} and Trerotola, {Scott O.} and Wolf, {Gerald L.} and Rombeau, {John L.}",

year = "1985",

month = jul,

doi = "10.1016/0022-4804(85)90156-8",

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T1 - The identification of experimentally induced appendicitis using in vitro nuclear magnetic resonance

AU - Jacobs, Danny O.

AU - Clarke, John R.

AU - Settle, R. G.

AU - Sachdeva, A. K.

AU - Wheeler, James E.

AU - Trerotola, Scott O.

AU - Wolf, Gerald L.

AU - Rombeau, John L.

PY - 1985/7

Y1 - 1985/7

N2 - Appendicitis was induced in six New Zealand white rabbits. The appendices from these animals had significantly higher spin-lattice relaxation times, T1, as determined in vitro by nuclear magnetic resonance (NMR) (10 controls vs 6 experimentals, 413 ± 23 vs 455 ± 41, X ± SD, P < (0.02). T1 correlated significantly with the water content of the appendiceal tissue (P < 0.001). These findings suggest that in vivo NMR imaging techniques weighted on T1 might be able to identify human appendicitis noninvasively by detecting localized edema.

AB - Appendicitis was induced in six New Zealand white rabbits. The appendices from these animals had significantly higher spin-lattice relaxation times, T1, as determined in vitro by nuclear magnetic resonance (NMR) (10 controls vs 6 experimentals, 413 ± 23 vs 455 ± 41, X ± SD, P < (0.02). T1 correlated significantly with the water content of the appendiceal tissue (P < 0.001). These findings suggest that in vivo NMR imaging techniques weighted on T1 might be able to identify human appendicitis noninvasively by detecting localized edema.

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JF - Journal of Surgical Research

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The identification of experimentally induced appendicitis using in vitro nuclear magnetic resonance

Abstract

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