TY - JOUR
T1 - The histopathologic features of lithium-associated thyroiditis
AU - Kontozoglou, Theodosios
AU - Mambo, Nobby
PY - 1983/8
Y1 - 1983/8
N2 - The case of a 62-year-old woman with lithium-associated thyroiditis is presented. Lithium can produce goiters associated with hypothyroidism and, less commonly, hyperthyroidism and euthyroidism. The characteristic histopathologic features of the affected thyroid gland included fibrosis, lymphoid follicles with atrophy, and hyperplasia of thyroid follicles. The pathogenetic mechanism appears to be immunologic, with lithium acting as a haptene with a thyroid antigen to induce an "autoimmune" type of thyroiditis.
AB - The case of a 62-year-old woman with lithium-associated thyroiditis is presented. Lithium can produce goiters associated with hypothyroidism and, less commonly, hyperthyroidism and euthyroidism. The characteristic histopathologic features of the affected thyroid gland included fibrosis, lymphoid follicles with atrophy, and hyperplasia of thyroid follicles. The pathogenetic mechanism appears to be immunologic, with lithium acting as a haptene with a thyroid antigen to induce an "autoimmune" type of thyroiditis.
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U2 - 10.1016/S0046-8177(83)80150-6
DO - 10.1016/S0046-8177(83)80150-6
M3 - Article
C2 - 6873938
AN - SCOPUS:0020503539
SN - 0046-8177
VL - 14
SP - 737
EP - 739
JO - Human Pathology
JF - Human Pathology
IS - 8
ER -