The histological interpretation of high frequency cutaneous ultrasound imaging

Stephen M. Milner, Omeed M. Memar, Giulio Gherardini, John C.D. Bennett, Linda G. Phillips

Research output: Contribution to journalArticlepeer-review

21 Scopus citations


BACKGROUND. High frequency, high resolution B-scan ultrasound imaging (US) has been used to assess skin. The use of US is limited because of difficulty interpreting the various echoes. OBJECTIVES. To correlate the appearance of constant US echoes with histology in normal human skin. METHODS. Normal skin from eight volunteers was scanned with US at a frequency of 20-25 MHz, prior to excision for clinical reasons. The echogenic bands of the skin and histological measurements of various layers were related statistically. RESULTS. Three constant echogenic bands were identified, which correlated with skin surface, dermis, and subcutaneous fascia. CONCLUSION. The correct interpretation of echogenic bands in normal skin allows for the US to be more reliably used for assessment of skill disorders.

Original languageEnglish (US)
Pages (from-to)43-45
Number of pages3
JournalDermatologic Surgery
Issue number1
StatePublished - 1997

ASJC Scopus subject areas

  • Surgery
  • Dermatology


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