TY - JOUR
T1 - The ethics of fertility preservation for pediatric patients with differences (disorders) of sex development
AU - Campo-Engelstein, Lisa
AU - Chen, Diane
AU - Baratz, Arlene B.
AU - Johnson, Emilie K.
AU - Finlayson, Courtney
N1 - Publisher Copyright:
© 2017 Endocrine Society.
PY - 2017/6
Y1 - 2017/6
N2 - Differences (disorders) of sex development are diverse conditions with variations in chromosomal, gonadal, and/or genital development. Fertility potential in this population is variable. Recent investigations into fertility potential in those previously thought to be infertile suggest that the majority may have fertility potential through experimental protocols. Fertility preservation may be more successful if pursued in childhood. As fertility research and techniques advance, it is important to carefully consider pediatric ethical issues specific to this population, including gonadectomy, consent/assent, experimental treatment and false hope, cost and insurance coverage, genetic transmission to offspring, and gender dysphoria.
AB - Differences (disorders) of sex development are diverse conditions with variations in chromosomal, gonadal, and/or genital development. Fertility potential in this population is variable. Recent investigations into fertility potential in those previously thought to be infertile suggest that the majority may have fertility potential through experimental protocols. Fertility preservation may be more successful if pursued in childhood. As fertility research and techniques advance, it is important to carefully consider pediatric ethical issues specific to this population, including gonadectomy, consent/assent, experimental treatment and false hope, cost and insurance coverage, genetic transmission to offspring, and gender dysphoria.
KW - Differences (disorders) of sex development
KW - Ethics
KW - Fertility preservation
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U2 - 10.1210/js.2017-00110
DO - 10.1210/js.2017-00110
M3 - Article
AN - SCOPUS:85044086432
SN - 2472-1972
VL - 1
SP - 638
EP - 645
JO - Journal of the Endocrine Society
JF - Journal of the Endocrine Society
IS - 6
ER -