The endogenous sub-type of depression: A study of its internal construct validity

M. A. Young; W. A. Scheftner; G. L. Klerman; N. C. Andreasen; R. M. Hirschfeld

doi:10.1192/bjp.148.3.257

The endogenous sub-type of depression: A study of its internal construct validity

M. A. Young, W. A. Scheftner, G. L. Klerman, N. C. Andreasen, R. M. Hirschfeld

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55 Scopus citations

Abstract

The internal construct validity of the endogenous sub-type of major depression was investigated by statistically modelling the RDC endogenous and DSM-III melancholia diagnostic criteria. Data consisted of symptom ratings on 788 patients with major depression from NIMH Collaborative Depression Study. Results indicated that the symptoms in the criteria do not specify a dichotomous classification, melancholic-non-melancholic or endogenous-nonendogenous. Results did not support the existance of two sub-typings, one related to anhedonia, and one related to vegetative symptoms. The vegetative sub-type rarely occurred in non-anhedonic patients. Previous studies may have found support for a simple endogenous sub-type because of this hierarchical relationship and as a result of methodological differences.

Original language	English (US)
Pages (from-to)	257-267
Number of pages	11
Journal	British Journal of Psychiatry
Volume	148
Issue number	MAR.
DOIs	https://doi.org/10.1192/bjp.148.3.257
State	Published - 1986
Externally published	Yes

ASJC Scopus subject areas

Psychiatry and Mental health

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abstract = "The internal construct validity of the endogenous sub-type of major depression was investigated by statistically modelling the RDC endogenous and DSM-III melancholia diagnostic criteria. Data consisted of symptom ratings on 788 patients with major depression from NIMH Collaborative Depression Study. Results indicated that the symptoms in the criteria do not specify a dichotomous classification, melancholic-non-melancholic or endogenous-nonendogenous. Results did not support the existance of two sub-typings, one related to anhedonia, and one related to vegetative symptoms. The vegetative sub-type rarely occurred in non-anhedonic patients. Previous studies may have found support for a simple endogenous sub-type because of this hierarchical relationship and as a result of methodological differences.",

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AU - Scheftner, W. A.

AU - Klerman, G. L.

AU - Andreasen, N. C.

AU - Hirschfeld, R. M.

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AB - The internal construct validity of the endogenous sub-type of major depression was investigated by statistically modelling the RDC endogenous and DSM-III melancholia diagnostic criteria. Data consisted of symptom ratings on 788 patients with major depression from NIMH Collaborative Depression Study. Results indicated that the symptoms in the criteria do not specify a dichotomous classification, melancholic-non-melancholic or endogenous-nonendogenous. Results did not support the existance of two sub-typings, one related to anhedonia, and one related to vegetative symptoms. The vegetative sub-type rarely occurred in non-anhedonic patients. Previous studies may have found support for a simple endogenous sub-type because of this hierarchical relationship and as a result of methodological differences.

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The endogenous sub-type of depression: A study of its internal construct validity

Abstract

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