The cell biology of acute itch

Dustin Green, Xinzhong Dong

Research output: Contribution to journalArticlepeer-review

34 Scopus citations


Itch, the irritation we feel and the relief that comes from scratching, is an evolutionary warning system and defense against harmful environmental agents. Although once considered a subtype of pain, itch is now recognized as a unique sense, with its own distinct physiology and cell receptors. Here, we discuss recent advances in our understanding of itch and the molecular players that mediate this sensory modality.

Original languageEnglish (US)
Pages (from-to)155-161
Number of pages7
JournalJournal of Cell Biology
Issue number2
StatePublished - Apr 1 2016
Externally publishedYes

ASJC Scopus subject areas

  • Cell Biology


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