Streptococcus faecium outbreak in a neonatal intensive care unit

P. E. Coudron, C. G. Mayhall, R. R. Facklam, A. C. Spadora, V. A. Lamb, M. R. Lybrand, H. P. Dalton

Research output: Contribution to journalArticlepeer-review

65 Scopus citations


An outbreak of bacteremia and meningitis in a neonatal intensive care unit is described. Seven cases occurred in premature infants with severe underlying diseases. An epidemiological investigation failed to document the reservoir of the epidemic strain but suggested that its transmission among the infants was via the hands of hospital personnel. All patients had nasogastric tubes and multiple intravascular devices. Conventional biotyping of isolates failed to differentiation between isolates from infected patients and isolates recovered from prevalence surveys and from the environment. However, rapid identification systems (API-20S [Analytab Products, Plainview, N.Y.] and the AutoMicrobic system [Vitek Systems, Inc., Hazelwood, Mo.]) were able to distinguish isolates recovered from infected patients and hands of hospital personnel from isolates recovered during prevalence and environmental surveys and 29 isolates from widespread geographical areas. This is the first known report of a nosocomial neonatal outbreak of bacteremia and meningitis due to Streptococcus faecium; it underscores the importance of identifying streptococci to species level.

Original languageEnglish (US)
Pages (from-to)1044-1048
Number of pages5
JournalJournal of Clinical Microbiology
Issue number6
StatePublished - 1984
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology (medical)


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