TY - JOUR
T1 - Stereological evaluation of liver volume in living donor liver transplantation using MDCT via the Cavalieri method
AU - Duran, Cihan
AU - Aydinli, Bulent
AU - Tokat, Yaman
AU - Yuzer, Yildiray
AU - Kantarci, Mecit
AU - Akgun, Metin
AU - Polat, Kamil Yalcin
AU - Unal, Bünyami
AU - Killi, Refik
AU - Atamanalp, S. Selcuk
PY - 2007/5
Y1 - 2007/5
N2 - In living donor liver transplantation (LDLT), obtaining the precise volume of the graft is very important to decrease volume-related postoperative complications, especially in cases with suspected small-for size grafts. We used stereology based on the Cavalieri method (CM), a new method to measure liver graft volume, and compared the results with those obtained through intraoperative measurement (10M) and through multidetector computed tomography (MDCT) measurement. Liver volumes estimated using the 3 methods were well-correlated with each other (r2 = 0.94 and P < 0.001 for IOM and CM; r2 = 0.91 and P < 0.001 for IOM and MDCT, and r2 = 0.95 and P < 0.001 for CM and MDCT); however, they were different from each other (in descending order, 908 ± 124 cm3, 861 ± 121 CM3, and 777 ± 168 CM3 for MDCT, CM, and IOM, respectively). Although MDCT and CM overestimated the volumes, the results of CM were almost similar to those obtained via IOM. In conclusion, our results suggest that CM measured the liver graft volume more reliably. Thus, its use particularly in cases with suspected small-for-size graft, may prove useful.
AB - In living donor liver transplantation (LDLT), obtaining the precise volume of the graft is very important to decrease volume-related postoperative complications, especially in cases with suspected small-for size grafts. We used stereology based on the Cavalieri method (CM), a new method to measure liver graft volume, and compared the results with those obtained through intraoperative measurement (10M) and through multidetector computed tomography (MDCT) measurement. Liver volumes estimated using the 3 methods were well-correlated with each other (r2 = 0.94 and P < 0.001 for IOM and CM; r2 = 0.91 and P < 0.001 for IOM and MDCT, and r2 = 0.95 and P < 0.001 for CM and MDCT); however, they were different from each other (in descending order, 908 ± 124 cm3, 861 ± 121 CM3, and 777 ± 168 CM3 for MDCT, CM, and IOM, respectively). Although MDCT and CM overestimated the volumes, the results of CM were almost similar to those obtained via IOM. In conclusion, our results suggest that CM measured the liver graft volume more reliably. Thus, its use particularly in cases with suspected small-for-size graft, may prove useful.
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U2 - 10.1002/lt.21132
DO - 10.1002/lt.21132
M3 - Article
C2 - 17457928
AN - SCOPUS:34249032087
SN - 1527-6465
VL - 13
SP - 693
EP - 698
JO - Liver Transplantation
JF - Liver Transplantation
IS - 5
ER -