Small and wide angle backscattering from rabbit cornea measured ex vivo by optical coherence tomography and confocal microscopy

Alexander I. Kholodnykh, Sergey Yu Treschev, Massoud Motamedi

Research output: Contribution to journalConference articlepeer-review

Abstract

Results of comparative ex vivo measurements of backscattering from rabbit cornea made by optical coherency tomography and confocal microscopy strongly suggests the existence of small angle backscattering from the cornea. Apparently, this is associated with a zero order peak of diffraction on the corneal fibril "lattice" structure, which was first suggested by D. Maurice in 1957 as a physical basis of corneal transparency. By using water suspension of polystyrene spheres as a scattering standard, absolute values of backscattering coefficients of normally hydrated cornea for wide and small angle backscattering and degree of fibrils arrangement could be estimated.

Original languageEnglish (US)
Article number53
Pages (from-to)318-324
Number of pages7
JournalProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume5690
DOIs
StatePublished - 2005
EventCoherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine IX - San Jose, CA, United States
Duration: Jan 23 2005Jan 26 2005

Keywords

  • Corneal backscattering
  • Corneal hydration control
  • Fibrillar order
  • Noninvasive monitoring
  • OCT

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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