TY - JOUR
T1 - Skeletal and Soft Tissue Sarcomas
T2 - Treatment With Adjuvant Immunotherapy
AU - Townsend, Courtney M.
AU - Eilber, Frederick R.
AU - Morton, Donald L.
PY - 1976/11/8
Y1 - 1976/11/8
N2 - Because there is evidence for an active immunologic response against sarcoma, a clinical trial of adjuvant immunotherapy using bacillus Calmette-Guérin (BCG) and tumor cell vaccine was begun. Eleven of 18 patients with localized soft tissue sarcoma who received immunotherapy are free of disease, compared to only 5 of 15 treated by operation alone who are free of disease. Furthermore, immunotherapy also prolonged the median disease-free interval from 7.3 months to 15 months in the patients who experienced recurrence of their disease.
AB - Because there is evidence for an active immunologic response against sarcoma, a clinical trial of adjuvant immunotherapy using bacillus Calmette-Guérin (BCG) and tumor cell vaccine was begun. Eleven of 18 patients with localized soft tissue sarcoma who received immunotherapy are free of disease, compared to only 5 of 15 treated by operation alone who are free of disease. Furthermore, immunotherapy also prolonged the median disease-free interval from 7.3 months to 15 months in the patients who experienced recurrence of their disease.
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U2 - 10.1001/jama.1976.03270200025023
DO - 10.1001/jama.1976.03270200025023
M3 - Article
C2 - 989809
AN - SCOPUS:0017180548
SN - 0098-7484
VL - 236
SP - 2187
EP - 2189
JO - JAMA: The Journal of the American Medical Association
JF - JAMA: The Journal of the American Medical Association
IS - 19
ER -