TY - JOUR
T1 - Sinonasal malignancies
AU - Resto, Vicente A.
AU - Deschler, Daniel G.
PY - 2004/4
Y1 - 2004/4
N2 - Sinonasal malignancies are highly heterogeneous lesions that are challenging to diagnose, treat, and follow clinically. Outcomes remain relatively poor and are associated with late diagnosis, difficult surgical anatomy, and a lack of effective adjuvant modalities of treatment. New multimodal treatment protocols addressed to specific tumor entities are being assessed with promising results. Because of the relative rarity of these lesions, however, progress is slow. The best therapeutic outcomes are achieved in the setting of early diagnosis combined with a meticulous, comprehensive, multidisciplinary approach to the management of these complex tumors.
AB - Sinonasal malignancies are highly heterogeneous lesions that are challenging to diagnose, treat, and follow clinically. Outcomes remain relatively poor and are associated with late diagnosis, difficult surgical anatomy, and a lack of effective adjuvant modalities of treatment. New multimodal treatment protocols addressed to specific tumor entities are being assessed with promising results. Because of the relative rarity of these lesions, however, progress is slow. The best therapeutic outcomes are achieved in the setting of early diagnosis combined with a meticulous, comprehensive, multidisciplinary approach to the management of these complex tumors.
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U2 - 10.1016/S0030-6665(03)00159-2
DO - 10.1016/S0030-6665(03)00159-2
M3 - Review article
C2 - 15064075
AN - SCOPUS:1842424690
SN - 0030-6665
VL - 37
SP - 473
EP - 487
JO - Otolaryngologic Clinics of North America
JF - Otolaryngologic Clinics of North America
IS - 2
ER -