TY - JOUR
T1 - Short report
T2 - Rickettsia felis outer membrane protein A: A potential tool for diagnosis of patients with flea-borne spotted fever
AU - Zavala-Castro, Jorge E.
AU - Dzul-Rosado, Karla R.
AU - León, Juan José Arias
AU - Walker, David H.
AU - Zavala-Velázquez, Jorge E.
PY - 2008/12
Y1 - 2008/12
N2 - Rickettsia felis infection in humans has been detected worldwide, causing an illness that could be confused with other viral and bacterial infections such as dengue fever. Despite the high incidence of infection in humans, reservoirs, and vectors, the definitive diagnosis of R. felis infection currently requires polymerase chain reaction and sequencing because its antigens are closely related to other rickettsiae, making serologic diagnosis problematic. In this work, we report the immune reactivity of sera from four patients infected with R. felis with recombinant peptides representing regions of outer membrane protein A of R. felis.
AB - Rickettsia felis infection in humans has been detected worldwide, causing an illness that could be confused with other viral and bacterial infections such as dengue fever. Despite the high incidence of infection in humans, reservoirs, and vectors, the definitive diagnosis of R. felis infection currently requires polymerase chain reaction and sequencing because its antigens are closely related to other rickettsiae, making serologic diagnosis problematic. In this work, we report the immune reactivity of sera from four patients infected with R. felis with recombinant peptides representing regions of outer membrane protein A of R. felis.
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U2 - 10.4269/ajtmh.2008.79.903
DO - 10.4269/ajtmh.2008.79.903
M3 - Article
C2 - 19052301
AN - SCOPUS:57649180806
SN - 0002-9637
VL - 79
SP - 903
EP - 906
JO - American Journal of Tropical Medicine and Hygiene
JF - American Journal of Tropical Medicine and Hygiene
IS - 6
ER -