Severe ciprofloxacin-associated pseudomembranous colitis in an eight-year-old child

Carlos A. Angel, Justtin Green, Leonard Swischuk, Janak Patel

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Clostridium difficile is the principal cause of antibiotic-associated diarrhea and pseudomembranous enterocolitis in children. A case of severe pseudomembranous colitis developing in an 8-year-old child who had received oral ciprofloxacin therapy as part of an investigational protocol is presented. The safety and efficacy of fluoroquinolones in children has not yet been established. Use of these antibiotics in children outside investigational protocols ("off-label" use) as oral antipseudomonas agents is discouraged.

Original languageEnglish (US)
Pages (from-to)1590-1592
Number of pages3
JournalJournal of Pediatric Surgery
Issue number10
StatePublished - Oct 2004


  • Clostridium difficile
  • Pseudomembranous colitis
  • antibiotic-induced diarrhea
  • ciprofloxacin
  • fluoroquinolones

ASJC Scopus subject areas

  • Surgery
  • Pediatrics, Perinatology, and Child Health


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