Seventy-four-year-old woman with myelodysplastic syndrome and splenomegaly

Alison Motosue; Jack Alperin; Mohamed T. Elghetany; Rana Bonds

doi:10.2500/aap.2010.31.3300

Seventy-four-year-old woman with myelodysplastic syndrome and splenomegaly

Alison Motosue, Jack Alperin, Mohamed T. Elghetany, Rana Bonds

Internal Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

We present a 74-year-old woman with a recent diagnosis of myelodysplastic syndrome who presented with left upper quadrant abdominal pain and fatigue with significant splenomegaly, anemia, and thrombocytopenia. She underwent splenectomy and bone marrow biopsy. Pathology of both spleen and bone marrow revealed an unusual diagnosis. A review of the differential diagnosis, laboratory tests, nature of the underlying disease, and treatment are provided.

Original language	English (US)
Pages (from-to)	252-257
Number of pages	6
Journal	Allergy and Asthma Proceedings
Volume	31
Issue number	3
DOIs	https://doi.org/10.2500/aap.2010.31.3300
State	Published - May 2010

Keywords

D816V
Hematologic non-mast cell lineage disease
Hypersplenism
Mast cells
Mastocytosis
Myelodysplastic syndrome
Splenomegaly
Systemic mastocytosis with associated clonal
Urticaria pigmentosa

ASJC Scopus subject areas

Immunology and Allergy
Pulmonary and Respiratory Medicine

Access to Document

10.2500/aap.2010.31.3300

Cite this

@article{2791e26c38e04c1d988acee09a79e9b9,

title = "Seventy-four-year-old woman with myelodysplastic syndrome and splenomegaly",

abstract = "We present a 74-year-old woman with a recent diagnosis of myelodysplastic syndrome who presented with left upper quadrant abdominal pain and fatigue with significant splenomegaly, anemia, and thrombocytopenia. She underwent splenectomy and bone marrow biopsy. Pathology of both spleen and bone marrow revealed an unusual diagnosis. A review of the differential diagnosis, laboratory tests, nature of the underlying disease, and treatment are provided.",

keywords = "D816V, Hematologic non-mast cell lineage disease, Hypersplenism, Mast cells, Mastocytosis, Myelodysplastic syndrome, Splenomegaly, Systemic mastocytosis with associated clonal, Urticaria pigmentosa",

author = "Alison Motosue and Jack Alperin and Elghetany, {Mohamed T.} and Rana Bonds",

year = "2010",

month = may,

doi = "10.2500/aap.2010.31.3300",

language = "English (US)",

volume = "31",

pages = "252--257",

journal = "Allergy and Asthma Proceedings",

issn = "1088-5412",

publisher = "OceanSide Publications Inc.",

number = "3",

}

TY - JOUR

T1 - Seventy-four-year-old woman with myelodysplastic syndrome and splenomegaly

AU - Motosue, Alison

AU - Alperin, Jack

AU - Elghetany, Mohamed T.

AU - Bonds, Rana

PY - 2010/5

Y1 - 2010/5

N2 - We present a 74-year-old woman with a recent diagnosis of myelodysplastic syndrome who presented with left upper quadrant abdominal pain and fatigue with significant splenomegaly, anemia, and thrombocytopenia. She underwent splenectomy and bone marrow biopsy. Pathology of both spleen and bone marrow revealed an unusual diagnosis. A review of the differential diagnosis, laboratory tests, nature of the underlying disease, and treatment are provided.

AB - We present a 74-year-old woman with a recent diagnosis of myelodysplastic syndrome who presented with left upper quadrant abdominal pain and fatigue with significant splenomegaly, anemia, and thrombocytopenia. She underwent splenectomy and bone marrow biopsy. Pathology of both spleen and bone marrow revealed an unusual diagnosis. A review of the differential diagnosis, laboratory tests, nature of the underlying disease, and treatment are provided.

KW - D816V

KW - Hematologic non-mast cell lineage disease

KW - Hypersplenism

KW - Mast cells

KW - Mastocytosis

KW - Myelodysplastic syndrome

KW - Splenomegaly

KW - Systemic mastocytosis with associated clonal

KW - Urticaria pigmentosa

UR - http://www.scopus.com/inward/record.url?scp=77953859326&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77953859326&partnerID=8YFLogxK

U2 - 10.2500/aap.2010.31.3300

DO - 10.2500/aap.2010.31.3300

M3 - Article

C2 - 20615327

AN - SCOPUS:77953859326

SN - 1088-5412

VL - 31

SP - 252

EP - 257

JO - Allergy and Asthma Proceedings

JF - Allergy and Asthma Proceedings

IS - 3

ER -

Seventy-four-year-old woman with myelodysplastic syndrome and splenomegaly

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this