@inproceedings{80eae5da6629422eacc9b8d89890bcaa,
title = "Sequence-dependent dynamics of DNA",
abstract = "The sequence-dependent high-frequency motion of a fluorescent base in DNA has been studied by picosecond time-resolved fluorescence depolarization measurements on a series of defined-sequence synthetic oligonucleotides of the type d[GCCXCCG] · d[CGG(AP)GGC], where X = T, A, G or C and AP is the fluorescent adenine analogue 2-aminopurine. The fluorescence anisotropy contained a rapidly decaying component that was due to restricted internal rotation of AP and a slowly decaying component due to overall tumbling. The tumbling correlation time varied with X in a manner that reflected the association state of the oligonucleotide strands. The internal motion dynamics of AP depended on the nature of the base-pairing interactions between AP and X.",
author = "Millar, {David P.} and Sowers, {Larry C.}",
year = "1990",
language = "English (US)",
isbn = "0819402451",
series = "Proceedings of SPIE - The International Society for Optical Engineering",
publisher = "Publ by Int Soc for Optical Engineering",
pages = "656--662",
editor = "Lakowicz, {Joseph F.}",
booktitle = "Proceedings of SPIE - The International Society for Optical Engineering",
note = "Time-Resolved Laser Spectroscopy in Biochemistry II ; Conference date: 15-01-1990 Through 17-01-1990",
}