Sensory Responsiveness in Siblings of Children with Autism Spectrum Disorders

Claudia L. Hilton; Alison Babb-Keeble; Erin Eitzmann Westover; Yi Zhang; Claire Adams; Diane M. Collins; Amol Karmarkar; Timothy A. Reistetter; John N. Constantino

doi:10.1007/s10803-016-2918-y

Sensory Responsiveness in Siblings of Children with Autism Spectrum Disorders

Claudia L. Hilton, Alison Babb-Keeble, Erin Eitzmann Westover, Yi Zhang, Claire Adams, Diane M. Collins, Amol Karmarkar, Timothy A. Reistetter, John N. Constantino

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

This study examined sensory responsiveness in unaffected siblings of children with autism spectrum disorder (ASD) and associations between sensory responsiveness and social severity. Sensory Profile Caregiver Questionnaires and Social Responsiveness Scales were completed by parents of 185 children between age 4 and 10.95 years. Significant differences were found between participants with ASD and controls, and between participants with ASD and unaffected siblings for all sensory quadrants and domains, but not between controls and unaffected siblings. Social responsiveness scores were significantly correlated with scores from most sensory profile categories. Sensory responsiveness as an endophenotype of ASD is not indicated from these findings; however, studies with larger numbers of unaffected siblings and controls are needed to confirm the null hypothesis.

Original language	English (US)
Pages (from-to)	3778-3787
Number of pages	10
Journal	Journal of Autism and Developmental Disorders
Volume	46
Issue number	12
DOIs	https://doi.org/10.1007/s10803-016-2918-y
State	Published - Dec 1 2016

Keywords

Autism
Endophenotype
Family
Genetics
Sensory responsiveness

ASJC Scopus subject areas

Developmental and Educational Psychology

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10.1007/s10803-016-2918-y

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title = "Sensory Responsiveness in Siblings of Children with Autism Spectrum Disorders",

abstract = "This study examined sensory responsiveness in unaffected siblings of children with autism spectrum disorder (ASD) and associations between sensory responsiveness and social severity. Sensory Profile Caregiver Questionnaires and Social Responsiveness Scales were completed by parents of 185 children between age 4 and 10.95 years. Significant differences were found between participants with ASD and controls, and between participants with ASD and unaffected siblings for all sensory quadrants and domains, but not between controls and unaffected siblings. Social responsiveness scores were significantly correlated with scores from most sensory profile categories. Sensory responsiveness as an endophenotype of ASD is not indicated from these findings; however, studies with larger numbers of unaffected siblings and controls are needed to confirm the null hypothesis.",

keywords = "Autism, Endophenotype, Family, Genetics, Sensory responsiveness",

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AU - Babb-Keeble, Alison

AU - Westover, Erin Eitzmann

AU - Zhang, Yi

AU - Adams, Claire

AU - Collins, Diane M.

AU - Karmarkar, Amol

AU - Reistetter, Timothy A.

AU - Constantino, John N.

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Sensory Responsiveness in Siblings of Children with Autism Spectrum Disorders

Abstract

Keywords

ASJC Scopus subject areas

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