TY - JOUR
T1 - Role of breast magnetic resonance imaging in determining breast as a source of unknown metastatic lymphadenopathy
AU - Henry-Tillman, Ronda S.
AU - Harms, Steven E.
AU - Westbrook, Kent C.
AU - Korourian, Soheila
AU - Klimberg, V. Suzanne
PY - 1999/12
Y1 - 1999/12
N2 - Background: Occult primary breast cancer (OPBC) represents less than 1% of breast cancer. In only a third of cases, mammography identifies a primary tumor. We hypothesized that rotating delivery of excitation off-resonance breast magnetic resonance imaging (MRI) would identify or exclude the breast as a primary site in patients with OPBC. Methods: In a retrospective review, 10 patients were identified with OPBC in which MRI was performed. Malignant appearing lesions were correlated with histopathologic findings at biopsy or surgery. Results: MRI identified the primary site in 8 of 10 cases as breast (80%), and excluded it in 2 cases. The extent of disease and location was accurately predicted when compared with histopathologic specimen. Conclusions: As we continue to focus on a cure of early breast cancer, it is imperative that diagnostic images become more sensitive and specific. MRI accurately predicted OPBC in this subset of patients. Copyright (C) 1999 Excerpta Medica Inc.
AB - Background: Occult primary breast cancer (OPBC) represents less than 1% of breast cancer. In only a third of cases, mammography identifies a primary tumor. We hypothesized that rotating delivery of excitation off-resonance breast magnetic resonance imaging (MRI) would identify or exclude the breast as a primary site in patients with OPBC. Methods: In a retrospective review, 10 patients were identified with OPBC in which MRI was performed. Malignant appearing lesions were correlated with histopathologic findings at biopsy or surgery. Results: MRI identified the primary site in 8 of 10 cases as breast (80%), and excluded it in 2 cases. The extent of disease and location was accurately predicted when compared with histopathologic specimen. Conclusions: As we continue to focus on a cure of early breast cancer, it is imperative that diagnostic images become more sensitive and specific. MRI accurately predicted OPBC in this subset of patients. Copyright (C) 1999 Excerpta Medica Inc.
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U2 - 10.1016/S0002-9610(99)00221-4
DO - 10.1016/S0002-9610(99)00221-4
M3 - Article
C2 - 10670860
AN - SCOPUS:0033381689
SN - 0002-9610
VL - 178
SP - 496
EP - 499
JO - American Journal of Surgery
JF - American Journal of Surgery
IS - 6
ER -