Role of γδ T cells in West Nile virus-induced encephalitis: Friend or foe?

Tian Wang

doi:10.1016/j.jneuroim.2011.10.004

Role of γδ T cells in West Nile virus-induced encephalitis: Friend or foe?

Tian Wang

Microbiology And Immunology

Research output: Contribution to journal › Review article › peer-review

9 Scopus citations

Abstract

West Nile virus (WNV)-induced encephalitis has been a public health concern in North America over the past decade. No therapeutics or vaccines are available for human use. Studies in animal models have provided important information for investigations of WNV pathogenesis and the host immune response in humans. This article will give an overview of the role of γδ T cells, one of the non-classical T cell subsets in the murine model of WNV encephalitis.

Original language	English (US)
Pages (from-to)	22-27
Number of pages	6
Journal	Journal of Neuroimmunology
Volume	240-241
DOIs	https://doi.org/10.1016/j.jneuroim.2011.10.004
State	Published - Dec 15 2011

Keywords

Encephalitis
Gamma/delta T cells
West Nile virus

ASJC Scopus subject areas

Immunology and Allergy
Immunology
Neurology
Clinical Neurology

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10.1016/j.jneuroim.2011.10.004

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title = "Role of γδ T cells in West Nile virus-induced encephalitis: Friend or foe?",

abstract = "West Nile virus (WNV)-induced encephalitis has been a public health concern in North America over the past decade. No therapeutics or vaccines are available for human use. Studies in animal models have provided important information for investigations of WNV pathogenesis and the host immune response in humans. This article will give an overview of the role of γδ T cells, one of the non-classical T cell subsets in the murine model of WNV encephalitis.",

keywords = "Encephalitis, Gamma/delta T cells, West Nile virus",

author = "Tian Wang",

note = "Funding Information: I thank the members of the Wang lab for their contribution to understanding γδ T cells in West Nile virus infection. I also wish to thank Dr. Thomas Welte for allowing me to use his unpublished results. I thank Ms. Mardelle Susman for the help in preparing this manuscript. This work was supported by NIH grant R01AI072060 (to T. Wang).",

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T1 - Role of γδ T cells in West Nile virus-induced encephalitis

T2 - Friend or foe?

AU - Wang, Tian

N1 - Funding Information: I thank the members of the Wang lab for their contribution to understanding γδ T cells in West Nile virus infection. I also wish to thank Dr. Thomas Welte for allowing me to use his unpublished results. I thank Ms. Mardelle Susman for the help in preparing this manuscript. This work was supported by NIH grant R01AI072060 (to T. Wang).

PY - 2011/12/15

Y1 - 2011/12/15

N2 - West Nile virus (WNV)-induced encephalitis has been a public health concern in North America over the past decade. No therapeutics or vaccines are available for human use. Studies in animal models have provided important information for investigations of WNV pathogenesis and the host immune response in humans. This article will give an overview of the role of γδ T cells, one of the non-classical T cell subsets in the murine model of WNV encephalitis.

AB - West Nile virus (WNV)-induced encephalitis has been a public health concern in North America over the past decade. No therapeutics or vaccines are available for human use. Studies in animal models have provided important information for investigations of WNV pathogenesis and the host immune response in humans. This article will give an overview of the role of γδ T cells, one of the non-classical T cell subsets in the murine model of WNV encephalitis.

KW - Encephalitis

KW - Gamma/delta T cells

KW - West Nile virus

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AN - SCOPUS:83555177251

SN - 0165-5728

VL - 240-241

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JO - Journal of Neuroimmunology

JF - Journal of Neuroimmunology

ER -

Role of γδ T cells in West Nile virus-induced encephalitis: Friend or foe?

Abstract

Keywords

ASJC Scopus subject areas

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