Release of cholecystokinin in response to food and intraduodenal fat in pigs, dogs and man

P. Lilja, I. Wiener, K. Inoue, G. M. Fried, G. H. Greeley, J. C. Thompson

Research output: Contribution to journalArticlepeer-review

49 Scopus citations

Abstract

The present study was done to compare endogenous cholecystokinin-33 release in response to physiologic stimuli (meal, fat) in pigs, dogs and man. Plasma levels of cholecystokinin-33 were monitored using a radioimmunoassay for cholecystokinin which detects only cholecystokinin-33 and cholecystokinin-39. Ingestion of a meal caused release of cholecystokinin-33 within five, 20 and 120 minutes in man, pigs and dogs, respectively. Intraduodenal administration of corn oil resulted in a significant release of cholecystokinin-33 within 20 minutes in dogs, pigs and man.

Original languageEnglish (US)
Pages (from-to)557-561
Number of pages5
JournalSurgery Gynecology and Obstetrics
Volume159
Issue number6
StatePublished - 1984
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Obstetrics and Gynecology

Fingerprint

Dive into the research topics of 'Release of cholecystokinin in response to food and intraduodenal fat in pigs, dogs and man'. Together they form a unique fingerprint.

Cite this