Relapse of Legionnaires' Disease in a Renal Transplant Recipient

Kenneth L. Sanders, David H. Walker, Terrence J. Lee

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


We describe a 44-year-old man who recently received a cadaveric renal transplant and had a relapse of Legionnaires' disease after an appropriate course of therapy. The relapse occurred within two weeks after completion of a three-week course of therapy with erythromycin stearate. A transbronchial biopsy specimen was positive for Legionella pneumophila by direct immunofluorescence, although the Dieterle silver impregnation stain was negative. The patient responded to a repeated course of erythromycin for an additional 21 days, and no further sequelae or relapses have been noted. The importance of early rapid diagnostic modalities in the immunocompromised patient is emphasized, and the need to consider the possibility of relapse after effective therapy is warranted.

Original languageEnglish (US)
Pages (from-to)833-834
Number of pages2
JournalArchives of Internal Medicine
Issue number6
StatePublished - Jun 1980
Externally publishedYes

ASJC Scopus subject areas

  • Internal Medicine


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