Reference standards and the physiologic significance of the pregnant goat (Capra hircus) as a human model in obstetrical research

John H. Cissik; Gary D. Hankins; Russell R. Snyder; William J. Ehler; Wayne A. Pierson

doi:10.1016/0300-9629(87)90076-4

Reference standards and the physiologic significance of the pregnant goat (Capra hircus) as a human model in obstetrical research

John H. Cissik, Gary D. Hankins, Russell R. Snyder, William J. Ehler, Wayne A. Pierson

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6 Scopus citations

Abstract

1. 1. Amniotic fluid, cerebrospinal fluid, serum, and urine chemistries; respiratory rate and arterial and mixed venous blood gases; heart rate, hematocrit, and cardiac output; and arterial, pulmonary artery, central venous and pulmonary wedge pressures were measured in 20 pregnant adult goats of 19.5-34 kg body weight. 2. 2. Arithmetic means, standard deviations, and coefficients of variation were calculated to develop reference values; in addition, the 95% confidence limits for ranges were established. 3. 3. Comparison of derived data with that from non-pregnant goats shows changes similar to those seen when examining pregnant and non-pregnant humans. 4. 4. These results indicate the pregnant goat is an acceptable model for human obstetrical research.

Original language	English (US)
Pages (from-to)	533-537
Number of pages	5
Journal	Comparative Biochemistry and Physiology -Part A : Molecular and Integrative Physiology
Volume	88
Issue number	3
DOIs	https://doi.org/10.1016/0300-9629(87)90076-4
State	Published - 1987
Externally published	Yes

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Physiology

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Reference standards and the physiologic significance of the pregnant goat (Capra hircus) as a human model in obstetrical research. / Cissik, John H.; Hankins, Gary D.; Snyder, Russell R. et al.
In: Comparative Biochemistry and Physiology -Part A : Molecular and Integrative Physiology, Vol. 88, No. 3, 1987, p. 533-537.

Research output: Contribution to journal › Article › peer-review

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abstract = "1. 1. Amniotic fluid, cerebrospinal fluid, serum, and urine chemistries; respiratory rate and arterial and mixed venous blood gases; heart rate, hematocrit, and cardiac output; and arterial, pulmonary artery, central venous and pulmonary wedge pressures were measured in 20 pregnant adult goats of 19.5-34 kg body weight. 2. 2. Arithmetic means, standard deviations, and coefficients of variation were calculated to develop reference values; in addition, the 95% confidence limits for ranges were established. 3. 3. Comparison of derived data with that from non-pregnant goats shows changes similar to those seen when examining pregnant and non-pregnant humans. 4. 4. These results indicate the pregnant goat is an acceptable model for human obstetrical research.",

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AU - Ehler, William J.

AU - Pierson, Wayne A.

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Reference standards and the physiologic significance of the pregnant goat (Capra hircus) as a human model in obstetrical research

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