Recurrent Respiratory Papillomatosis

Naren N. Venkatesan; Harold S. Pine; Michael Underbrink

doi:10.1016/j.otc.2012.03.006

Recurrent Respiratory Papillomatosis

Naren N. Venkatesan, Harold S. Pine, Michael Underbrink

Research output: Contribution to journal › Review article › peer-review

73 Scopus citations

Abstract

Recurrent respiratory papillomatosis (RRP) is a rare, benign disease with no known cure. RRP is caused by infection of the upper aerodigestive tract with the human papillomavirus (HPV). Passage through the birth canal is thought to be the initial transmission event, but infection may occur in utero. HPV vaccines have helped to provide protection from cervical cancer; however, their role in the prevention of RRP is undetermined. Clinical presentation of initial symptoms of RRP may be subtle. RRP course varies, and current management focuses on surgical debulking of papillomatous lesions with or without concurrent adjuvant therapy.

Original language	English (US)
Pages (from-to)	671-694
Number of pages	24
Journal	Otolaryngologic Clinics of North America
Volume	45
Issue number	3
DOIs	https://doi.org/10.1016/j.otc.2012.03.006
State	Published - Jun 2012
Externally published	Yes

Keywords

Aerodigestive tract
Human papillomavirus
Papillomas
Papillomatosis

ASJC Scopus subject areas

Otorhinolaryngology

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10.1016/j.otc.2012.03.006

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title = "Recurrent Respiratory Papillomatosis",

abstract = "Recurrent respiratory papillomatosis (RRP) is a rare, benign disease with no known cure. RRP is caused by infection of the upper aerodigestive tract with the human papillomavirus (HPV). Passage through the birth canal is thought to be the initial transmission event, but infection may occur in utero. HPV vaccines have helped to provide protection from cervical cancer; however, their role in the prevention of RRP is undetermined. Clinical presentation of initial symptoms of RRP may be subtle. RRP course varies, and current management focuses on surgical debulking of papillomatous lesions with or without concurrent adjuvant therapy.",

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AU - Venkatesan, Naren N.

AU - Pine, Harold S.

AU - Underbrink, Michael

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AB - Recurrent respiratory papillomatosis (RRP) is a rare, benign disease with no known cure. RRP is caused by infection of the upper aerodigestive tract with the human papillomavirus (HPV). Passage through the birth canal is thought to be the initial transmission event, but infection may occur in utero. HPV vaccines have helped to provide protection from cervical cancer; however, their role in the prevention of RRP is undetermined. Clinical presentation of initial symptoms of RRP may be subtle. RRP course varies, and current management focuses on surgical debulking of papillomatous lesions with or without concurrent adjuvant therapy.

KW - Aerodigestive tract

KW - Human papillomavirus

KW - Papillomas

KW - Papillomatosis

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JO - Otolaryngologic Clinics of North America

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ER -

Recurrent Respiratory Papillomatosis

Abstract

Keywords

ASJC Scopus subject areas

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