TY - JOUR
T1 - Recent vaccine development for human metapneumovirus
AU - Ren, J.
AU - Phan, T.
AU - Bao, X.
N1 - Publisher Copyright:
© 2015 The Authors.
PY - 2015/7/1
Y1 - 2015/7/1
N2 - Human metapneumovirus (hMPV) and respiratory syncytial virus, its close family member, are two major causes of lower respiratory tract infection in the paediatric population. hMPV is also acommon cause of worldwide morbidity and mortality in immunocompromised patients and older adults. Repeated infections occur often, demonstrating a heavy medical burden. However, there is currently no hMPV-specific prevention treatment. This review focuses on the current literature on hMPV vaccine development. We believe that a better understanding of the role(s) of viral proteins in host responses might lead to efficient prophylactic vaccine development.
AB - Human metapneumovirus (hMPV) and respiratory syncytial virus, its close family member, are two major causes of lower respiratory tract infection in the paediatric population. hMPV is also acommon cause of worldwide morbidity and mortality in immunocompromised patients and older adults. Repeated infections occur often, demonstrating a heavy medical burden. However, there is currently no hMPV-specific prevention treatment. This review focuses on the current literature on hMPV vaccine development. We believe that a better understanding of the role(s) of viral proteins in host responses might lead to efficient prophylactic vaccine development.
UR - http://www.scopus.com/inward/record.url?scp=84938406908&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84938406908&partnerID=8YFLogxK
U2 - 10.1099/vir.0.000083
DO - 10.1099/vir.0.000083
M3 - Review article
C2 - 25667325
AN - SCOPUS:84938406908
SN - 0022-1317
VL - 96
SP - 1515
EP - 1520
JO - Journal of General Virology
JF - Journal of General Virology
IS - 7
ER -