Proteomics Approach to Identify Biomarkers in Neurodegenerative Diseases

Annapurna Nayak; Gregory Salt; Sunil K. Verma; Uday Kishore

doi:10.1016/bs.irn.2015.05.003

Proteomics Approach to Identify Biomarkers in Neurodegenerative Diseases

Annapurna Nayak, Gregory Salt, Sunil K. Verma, Uday Kishore

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

5 Scopus citations

Abstract

This chapter examines the use of proteomics in understanding pathogenesis and identifying possible biomarkers in a range of neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, and prion diseases. We have attempted to look at the neuroproteomic approach from a biomarker discovery point of view. Novel biomarkers can pave the way for new therapeutic targets and lead us to a better understanding of the pathogenesis involved in the neurodegenerative diseases.

Original language	English (US)
Title of host publication	International Review of Neurobiology
Editors	Michael J. Hurley
Publisher	Academic Press Inc.
Pages	59-86
Number of pages	28
ISBN (Print)	9780128014806
DOIs	https://doi.org/10.1016/bs.irn.2015.05.003
State	Published - 2015
Externally published	Yes

Publication series

Name	International Review of Neurobiology
Volume	121
ISSN (Print)	0074-7742
ISSN (Electronic)	2162-5514

Keywords

Biomarker
Neurodegeneration
Neuroinflammation
Proteomic

ASJC Scopus subject areas

Clinical Neurology
Cellular and Molecular Neuroscience

Access to Document

10.1016/bs.irn.2015.05.003

Cite this

@inproceedings{edffb3b819374e82b43d5f9ab40ccff9,

title = "Proteomics Approach to Identify Biomarkers in Neurodegenerative Diseases",

abstract = "This chapter examines the use of proteomics in understanding pathogenesis and identifying possible biomarkers in a range of neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, and prion diseases. We have attempted to look at the neuroproteomic approach from a biomarker discovery point of view. Novel biomarkers can pave the way for new therapeutic targets and lead us to a better understanding of the pathogenesis involved in the neurodegenerative diseases.",

keywords = "Biomarker, Neurodegeneration, Neuroinflammation, Proteomic",

author = "Annapurna Nayak and Gregory Salt and Verma, {Sunil K.} and Uday Kishore",

year = "2015",

doi = "10.1016/bs.irn.2015.05.003",

language = "English (US)",

isbn = "9780128014806",

series = "International Review of Neurobiology",

publisher = "Academic Press Inc.",

pages = "59--86",

editor = "Hurley, {Michael J.}",

booktitle = "International Review of Neurobiology",

}

TY - GEN

T1 - Proteomics Approach to Identify Biomarkers in Neurodegenerative Diseases

AU - Nayak, Annapurna

AU - Salt, Gregory

AU - Verma, Sunil K.

AU - Kishore, Uday

PY - 2015

Y1 - 2015

N2 - This chapter examines the use of proteomics in understanding pathogenesis and identifying possible biomarkers in a range of neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, and prion diseases. We have attempted to look at the neuroproteomic approach from a biomarker discovery point of view. Novel biomarkers can pave the way for new therapeutic targets and lead us to a better understanding of the pathogenesis involved in the neurodegenerative diseases.

AB - This chapter examines the use of proteomics in understanding pathogenesis and identifying possible biomarkers in a range of neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, and prion diseases. We have attempted to look at the neuroproteomic approach from a biomarker discovery point of view. Novel biomarkers can pave the way for new therapeutic targets and lead us to a better understanding of the pathogenesis involved in the neurodegenerative diseases.

KW - Biomarker

KW - Neurodegeneration

KW - Neuroinflammation

KW - Proteomic

UR - http://www.scopus.com/inward/record.url?scp=84973412506&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84973412506&partnerID=8YFLogxK

U2 - 10.1016/bs.irn.2015.05.003

DO - 10.1016/bs.irn.2015.05.003

M3 - Conference contribution

C2 - 26315762

AN - SCOPUS:84973412506

SN - 9780128014806

T3 - International Review of Neurobiology

SP - 59

EP - 86

BT - International Review of Neurobiology

A2 - Hurley, Michael J.

PB - Academic Press Inc.

ER -

Proteomics Approach to Identify Biomarkers in Neurodegenerative Diseases

Abstract

Publication series

Keywords

ASJC Scopus subject areas

Access to Document

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