Protein hydration density: Theory, simulations and crystallography

B. Montgomery Pettitt, Vladimir A. Makarov, B. Kim Andrews

Research output: Contribution to journalArticlepeer-review

50 Scopus citations


Models of protein hydration are becoming increasingly more accurate in comparison with experimental data. The recent success of these models implies that the major features of the solvation layers are dominated by local correlations and that such correlations are universal. The excellent agreement between theoretical and experimental solvent electron density radial distributions marks a significant success in our ability to accurately model macromolecular hydration.

Original languageEnglish (US)
Pages (from-to)218-221
Number of pages4
JournalCurrent Opinion in Structural Biology
Issue number2
StatePublished - Apr 1998
Externally publishedYes

ASJC Scopus subject areas

  • Structural Biology
  • Molecular Biology


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