TY - JOUR
T1 - Prostate-specific antigen testing in men aged 40-64 years
T2 - Impact of publication of clinical trials
AU - Goodwin, James S.
AU - Tan, Alai
AU - Jaramillo, Elizabeth
AU - Kuo, Yong Fang
N1 - Funding Information:
This work was supported by the Cancer Prevention Research Institute of Texas (RP101207) and the National Cancer Institute at the National Institutes of Health (K05 CA134923). None of the authors have any conflicts of interest to report.
PY - 2013/5/15
Y1 - 2013/5/15
N2 - We assessed the impact of the publication of trials and changes in recommendations on the rates of prostate-specific antigen (PSA) screening in men aged 40 to 64 years by analyzing monthly medical claims for PSA testing in a commercial insurance database from 2001 to 2011, covering more than 1.5 million men in each year. The testing rates for men aged 40 to 49 years, 50 to 59 years, and 60 to 64 years were 12.1%, 32.7%, and 42.7%, respectively, in 2001 vs 15.7%, 34.2%, and 42.0%, respectively, in 2011. Men aged 40 to 49 years experienced a gradual increase in testing rate from 2001 through 2008 (annual change in PSA testing per 10 000 men [AC] = 4.37; P <. 001), which became flat from mid-2009 through 2011(AC = -0.06; P =.98). The slope of PSA testing rates did not change in men aged 50 to 59 years or 60 to 64 years with the publication of the results of the large trials in 2009 or with the subsequent changes in recommendations on PSA testing.
AB - We assessed the impact of the publication of trials and changes in recommendations on the rates of prostate-specific antigen (PSA) screening in men aged 40 to 64 years by analyzing monthly medical claims for PSA testing in a commercial insurance database from 2001 to 2011, covering more than 1.5 million men in each year. The testing rates for men aged 40 to 49 years, 50 to 59 years, and 60 to 64 years were 12.1%, 32.7%, and 42.7%, respectively, in 2001 vs 15.7%, 34.2%, and 42.0%, respectively, in 2011. Men aged 40 to 49 years experienced a gradual increase in testing rate from 2001 through 2008 (annual change in PSA testing per 10 000 men [AC] = 4.37; P <. 001), which became flat from mid-2009 through 2011(AC = -0.06; P =.98). The slope of PSA testing rates did not change in men aged 50 to 59 years or 60 to 64 years with the publication of the results of the large trials in 2009 or with the subsequent changes in recommendations on PSA testing.
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U2 - 10.1093/jnci/djt039
DO - 10.1093/jnci/djt039
M3 - Article
C2 - 23459245
AN - SCOPUS:84877993796
SN - 0027-8874
VL - 105
SP - 743
EP - 745
JO - Journal of the National Cancer Institute
JF - Journal of the National Cancer Institute
IS - 10
ER -