TY - JOUR
T1 - Prevalence of dust mites in the homes of people with asthma living in eight different geographic areas of the United States
AU - Arlian, Larry G.
AU - Bernstein, David
AU - Bernstein, I. L.
AU - Friedman, Stuart
AU - Grant, Andrew
AU - Lieberman, Philip
AU - Lopez, Manuel
AU - Metzger, James
AU - Platts-Mills, Thomas
AU - Schatz, Michael
AU - Spector, Sheldon
AU - Wasserman, Stephen I.
AU - Zeiger, Robert S.
N1 - Funding Information:
From the Department of Biological Sciences, Wright State Uni-versity, Dayton, ~ the University of Cincinnati Medical Center, Cincinnati, 2 the Medical Center at Delray, Delray Beach, 3 the University of Texas Medical Branch, Galveston, 4 the School of Medicine, University of Tennessee, Memphis, 5 Tulane Medical School, New Orleans, 6 the School of Medicine, East Carolina University, Greenville, 7 the University of Virginia Medical Cen-ter, Charlottesville, 8 Southern California Permanente Medical Group, San Diego, 9 UCLA Medical Center, Los Angeles, "~ and UCSD Medical Center, San Diego. ~ Supported by grants AI-20565, AI-21984, AI-21987, AI-21991, and MOI-RR-00073 from the National Institute of Allergy and Infectious Disease (National Institutes of Health, Bethesda, Md.).
PY - 1992/9
Y1 - 1992/9
N2 - The density and species prevalence of dust mites were determined at various times over a 5-year-period in 252 homes of dust mite sensitive people with asthma who lived in eight geographic areas of the United States (Cincinnati, Ohio; New Orleans, La.; Memphis, Tenn.; Galveston, Texas; Greenville, N.C.; Delray Beach, Fla.; San Diego and Los Angeles, Calif.). The most common dust mites found in the homes were Dermatophagoides farinae (DF), D. pteronyssinus (DP), Euroglyphus maynei (EM), and Blomia tropicalis. All homes in all locations contained Dermatophagoides spp. mites, but few homes were populated exclusively by either DF or DP alone. Most homes (81.7%) were coinhabitated by both DF and DP. In coinhabited homes one species was predominant and usually made up at least 75% of the total mite population. Prevalence of the dominant or only species present varied between homes within a geographic area. EM occurred in significant numbers in 35.7% of homes in New Orleans, Memphis, Galveston, Delray Beach, and San Diego. Blomia tropicalis occurred in these same cities but in low densities. For all dust samples, only 13 homes of the 252 sampled had 100 or fewer mites/gm dust, which is considered to be the threshold for sensitivity. Most homes had average mite densities of 500 or more mites/gm dust. The results of the present study suggest a significant and widespread occurrence of both DF and DP. Therefore extracts of both mite species should be considered for diagnostic tests and immunotherapy. Significant levels of EM were present in some areas. Thus sensitivity to EM should be considered in these areas.
AB - The density and species prevalence of dust mites were determined at various times over a 5-year-period in 252 homes of dust mite sensitive people with asthma who lived in eight geographic areas of the United States (Cincinnati, Ohio; New Orleans, La.; Memphis, Tenn.; Galveston, Texas; Greenville, N.C.; Delray Beach, Fla.; San Diego and Los Angeles, Calif.). The most common dust mites found in the homes were Dermatophagoides farinae (DF), D. pteronyssinus (DP), Euroglyphus maynei (EM), and Blomia tropicalis. All homes in all locations contained Dermatophagoides spp. mites, but few homes were populated exclusively by either DF or DP alone. Most homes (81.7%) were coinhabitated by both DF and DP. In coinhabited homes one species was predominant and usually made up at least 75% of the total mite population. Prevalence of the dominant or only species present varied between homes within a geographic area. EM occurred in significant numbers in 35.7% of homes in New Orleans, Memphis, Galveston, Delray Beach, and San Diego. Blomia tropicalis occurred in these same cities but in low densities. For all dust samples, only 13 homes of the 252 sampled had 100 or fewer mites/gm dust, which is considered to be the threshold for sensitivity. Most homes had average mite densities of 500 or more mites/gm dust. The results of the present study suggest a significant and widespread occurrence of both DF and DP. Therefore extracts of both mite species should be considered for diagnostic tests and immunotherapy. Significant levels of EM were present in some areas. Thus sensitivity to EM should be considered in these areas.
KW - Blomia tropicalis
KW - Dermatophagoides farinae
KW - Dermatophagoides pteronyssinus
KW - Euroglyphus maynei
KW - allergenicity
KW - allergic disease
KW - asthma
KW - house dust mites
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UR - http://www.scopus.com/inward/citedby.url?scp=0026781588&partnerID=8YFLogxK
U2 - 10.1016/S0091-6749(05)80006-5
DO - 10.1016/S0091-6749(05)80006-5
M3 - Article
C2 - 1527314
AN - SCOPUS:0026781588
SN - 0091-6749
VL - 90
SP - 292
EP - 300
JO - The Journal of Allergy and Clinical Immunology
JF - The Journal of Allergy and Clinical Immunology
IS - 3 PART 1
ER -