Preliminary Evidence That Hantaan or a Closely Related Virus is Enzootic in Domestic Rodents

Theodore F. Tsai, Sally P. Bauer, Donna R. Sasso, Joseph B. Mccormick, Henry Bradford, Charles T. Caraway, Louise M. Mcfarland, Oscar Medrano, George Soulie, James W. Leduc, Gregory A. Smith, Lauren R. Bagley, Sherman E. Hasty, Karl M. Johnson, Pyung Woo Lee, Richard Yanagihara, Maryellen C. Franko, Herbert L. Amyx, Clarence J. Gibbs, D. Carleton GajdusekRobert Traub

Research output: Contribution to journalLetterpeer-review

40 Scopus citations


To the Editor: Rodent-borne viral nephropathy1 — known as epidemic hemorrhagic fever in Korea,2,3 hemorrhagic fever with renal syndrome in Central Europe and Russia,3 and nephropathia epidemica in Scandinavia4 — has not, to our knowledge, been reported in North America. We present preliminary data suggesting that Hantaan virus, the agent of rodent-borne viral nephropathy in Asia,5 or a closely related virus, infects domestic rats (Rattus norvegicus) in New Orleans, Louisiana. Serum collected from Louisiana rats that had been trapped in the course of surveillance for plague and murine typhus was examined for antibody to Hantaan virus by an indirect fluorescent-antibody.

Original languageEnglish (US)
Pages (from-to)623-625
Number of pages3
JournalNew England Journal of Medicine
Issue number10
StatePublished - Sep 2 1982
Externally publishedYes

ASJC Scopus subject areas

  • General Medicine


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