Prediction of 12-Month Neurodevelopmental Outcome From a 6-Month Neurologic Examination in Premature Infants

Susan R. Wildin, Karen Smith, Anne Anderson, Marilyn Woodside, Paul Swank, Susan Denson, Susan Landry

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

This study examined whether a neurologic examination at 6 months of age is predictive of neurodevelopmental outcome at 12 months in very-low-birth-weight (VLBW) infants. A neurologic examination and the Bayley Scales of Infant Development were performed at 6 and 12 months with VLBW infants and full-term (FT) controls. VLBW infants were categorized based on early medical complications. High-risk (HR) infants had diagnoses of bronchopulmonary dysplasia, pulmonary immaturity, grade III or IV intraventricular hemorrhage, and/or periventricular leukomalacia. VLBW infants with other diagnoses were placed in the low-risk (LR) group. Total neurologic scores (NS) improved over time for all three groups but improved more for HR infants, who had more abnormal NS at both time points; NS at 6 months predicted neurologic and developmental scores at 12 months for all three groups, but the relation between 6-and 12-month outcomes was strongest for the HR infants. The neurologic examination may be helpful in assessing VLBW infants‘ need for referral to early childhood intervention programs.

Original languageEnglish (US)
Pages (from-to)290-299
Number of pages10
JournalClinical pediatrics
Volume34
Issue number6
DOIs
StatePublished - Jun 1995
Externally publishedYes

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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