Pre-existing skin diseases as predictors of post-burn pruritus

Grace Obanigba, Jayson W. Jay, Steven Wolf, Georgiy Golovko, Juquan Song, Ann Obi, Tsola Efejuku, Dominique Johnson, Amina El Ayadi

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Post-burn pruritus (PBP) has been shown to adversely affect burn patients’ quality of life. However, the predictors of PBP are not known. We hypothesize a pre-existing pruritic skin diagnosis is associated with an increased risk of adverse outcomes following a burn injury. Methods: This retrospective study utilized data from the TriNetX electronic health record. Burn patients with a history of a pruritic skin disorder were compared to patients without a diagnosed skin disorder and the occurrence of pruritus was compared between the two cohorts. Results: Patients with pre-existing skin conditions were more likely to develop PBP. The risk of PBP was highest 1 year after injury. Stratification by percent TBSA burned, gender, race, and age showed an increased risk of PBP for females, Caucasians, older patients, and those with large burns. Conclusion: A pre-existing pruritic skin diagnosis is highly associated with developing pruritus following a burn injury.

Original languageEnglish (US)
JournalAmerican Journal of Surgery
DOIs
StateAccepted/In press - 2023

Keywords

  • Burn
  • Patients database
  • Pruritus
  • Quality of life
  • Skin disease

ASJC Scopus subject areas

  • Surgery

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