Potential therapeutic approach of intravenous immunoglobulin against COVID-19

Zahra Kolahchi, Hanye Sohrabi, Sara Ekrami Nasab, Hesan Jelodari Mamaghani, Maryam Keyfari Alamdari, Nima Rezaei

Research output: Contribution to journalReview articlepeer-review


Since the outbreak of the novel coronavirus disease (COVID-19), the therapeutic and management options to reduce the burden of the COVID-19 disease are under investigation. IVIG therapy is used as an effective treatment for immunodeficient patients and patients with inflammatory or autoimmune conditions. The therapeutic effect of IVIG in COVID-19 patients has been investigated. But, the results are controversial and some studies reported no benefit of IVIG therapy. More clinical trials on the effect of IVIG therapy in COVID-19 patients should be performed to establish a certain conclusion about IVIG effectiveness.

Original languageEnglish (US)
Article number105
JournalAllergy, Asthma and Clinical Immunology
Issue number1
StatePublished - Dec 2021
Externally publishedYes


  • Coronavirus disease
  • Hyperreactivity
  • Intravenous immunoglobulin
  • Respiratory syndromes
  • Treatment

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Pulmonary and Respiratory Medicine


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