Potential therapeutic approach of intravenous immunoglobulin against COVID-19

Zahra Kolahchi; Hanye Sohrabi; Sara Ekrami Nasab; Hesan Jelodari Mamaghani; Maryam Keyfari Alamdari; Nima Rezaei

doi:10.1186/s13223-021-00609-3

Potential therapeutic approach of intravenous immunoglobulin against COVID-19

Zahra Kolahchi, Hanye Sohrabi, Sara Ekrami Nasab, Hesan Jelodari Mamaghani, Maryam Keyfari Alamdari, Nima Rezaei

Research output: Contribution to journal › Review article › peer-review

Abstract

Since the outbreak of the novel coronavirus disease (COVID-19), the therapeutic and management options to reduce the burden of the COVID-19 disease are under investigation. IVIG therapy is used as an effective treatment for immunodeficient patients and patients with inflammatory or autoimmune conditions. The therapeutic effect of IVIG in COVID-19 patients has been investigated. But, the results are controversial and some studies reported no benefit of IVIG therapy. More clinical trials on the effect of IVIG therapy in COVID-19 patients should be performed to establish a certain conclusion about IVIG effectiveness.

Original language	English (US)
Article number	105
Journal	Allergy, Asthma and Clinical Immunology
Volume	17
Issue number	1
DOIs	https://doi.org/10.1186/s13223-021-00609-3
State	Published - Dec 2021
Externally published	Yes

Keywords

Coronavirus disease
Hyperreactivity
Intravenous immunoglobulin
Respiratory syndromes
Treatment

ASJC Scopus subject areas

Immunology and Allergy
Immunology
Pulmonary and Respiratory Medicine

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10.1186/s13223-021-00609-3

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title = "Potential therapeutic approach of intravenous immunoglobulin against COVID-19",

abstract = "Since the outbreak of the novel coronavirus disease (COVID-19), the therapeutic and management options to reduce the burden of the COVID-19 disease are under investigation. IVIG therapy is used as an effective treatment for immunodeficient patients and patients with inflammatory or autoimmune conditions. The therapeutic effect of IVIG in COVID-19 patients has been investigated. But, the results are controversial and some studies reported no benefit of IVIG therapy. More clinical trials on the effect of IVIG therapy in COVID-19 patients should be performed to establish a certain conclusion about IVIG effectiveness.",

keywords = "Coronavirus disease, Hyperreactivity, Intravenous immunoglobulin, Respiratory syndromes, Treatment",

author = "Zahra Kolahchi and Hanye Sohrabi and {Ekrami Nasab}, Sara and {Jelodari Mamaghani}, Hesan and {Keyfari Alamdari}, Maryam and Nima Rezaei",

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AU - Kolahchi, Zahra

AU - Sohrabi, Hanye

AU - Ekrami Nasab, Sara

AU - Jelodari Mamaghani, Hesan

AU - Keyfari Alamdari, Maryam

AU - Rezaei, Nima

PY - 2021/12

Y1 - 2021/12

N2 - Since the outbreak of the novel coronavirus disease (COVID-19), the therapeutic and management options to reduce the burden of the COVID-19 disease are under investigation. IVIG therapy is used as an effective treatment for immunodeficient patients and patients with inflammatory or autoimmune conditions. The therapeutic effect of IVIG in COVID-19 patients has been investigated. But, the results are controversial and some studies reported no benefit of IVIG therapy. More clinical trials on the effect of IVIG therapy in COVID-19 patients should be performed to establish a certain conclusion about IVIG effectiveness.

AB - Since the outbreak of the novel coronavirus disease (COVID-19), the therapeutic and management options to reduce the burden of the COVID-19 disease are under investigation. IVIG therapy is used as an effective treatment for immunodeficient patients and patients with inflammatory or autoimmune conditions. The therapeutic effect of IVIG in COVID-19 patients has been investigated. But, the results are controversial and some studies reported no benefit of IVIG therapy. More clinical trials on the effect of IVIG therapy in COVID-19 patients should be performed to establish a certain conclusion about IVIG effectiveness.

KW - Coronavirus disease

KW - Hyperreactivity

KW - Intravenous immunoglobulin

KW - Respiratory syndromes

KW - Treatment

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JF - Allergy, Asthma and Clinical Immunology

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Potential therapeutic approach of intravenous immunoglobulin against COVID-19

Abstract

Keywords

ASJC Scopus subject areas

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