Postexposure treatment of marburg virus infection

Thomas W. Geisbert; Lisa E. Hensley; Joan B. Geisbert; Anders Leung; Joshua C. Johnson; Allen Grolla; Heinz Feldmann

doi:10.3201/eid1607.100159

Postexposure treatment of marburg virus infection

Thomas W. Geisbert, Lisa E. Hensley, Joan B. Geisbert, Anders Leung, Joshua C. Johnson, Allen Grolla, Heinz Feldmann

Research output: Contribution to journal › Article › peer-review

60 Scopus citations

Abstract

Rhesus monkeys are protected from disease when a recombinant vesicular stomatitis virus-based vaccine is administered 20-30 min after infection with Marburg virus. We protected 5/6 monkeys when this vaccine was given 24 h after challenge; 2/6 animals were protected when the vaccine was administered 48 h postinfection.

Original language	English (US)
Pages (from-to)	1119-1122
Number of pages	4
Journal	Emerging infectious diseases
Volume	16
Issue number	7
DOIs	https://doi.org/10.3201/eid1607.100159
State	Published - Jul 2010
Externally published	Yes

ASJC Scopus subject areas

Epidemiology
Microbiology (medical)
Infectious Diseases

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10.3201/eid1607.100159

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title = "Postexposure treatment of marburg virus infection",

abstract = "Rhesus monkeys are protected from disease when a recombinant vesicular stomatitis virus-based vaccine is administered 20-30 min after infection with Marburg virus. We protected 5/6 monkeys when this vaccine was given 24 h after challenge; 2/6 animals were protected when the vaccine was administered 48 h postinfection.",

author = "Geisbert, {Thomas W.} and Hensley, {Lisa E.} and Geisbert, {Joan B.} and Anders Leung and Johnson, {Joshua C.} and Allen Grolla and Heinz Feldmann",

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AU - Geisbert, Thomas W.

AU - Hensley, Lisa E.

AU - Geisbert, Joan B.

AU - Leung, Anders

AU - Johnson, Joshua C.

AU - Grolla, Allen

AU - Feldmann, Heinz

PY - 2010/7

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AB - Rhesus monkeys are protected from disease when a recombinant vesicular stomatitis virus-based vaccine is administered 20-30 min after infection with Marburg virus. We protected 5/6 monkeys when this vaccine was given 24 h after challenge; 2/6 animals were protected when the vaccine was administered 48 h postinfection.

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Postexposure treatment of marburg virus infection

Abstract

ASJC Scopus subject areas

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