TY - JOUR
T1 - Phylogenetics and pathogenesis of early avian influenza viruses (H5N1), Nigeria
AU - Aiki-Raji, Comfort O.
AU - Aguilar, Patricia V.
AU - Kwon, Yong Kuk
AU - Goetz, Sue
AU - Suarez, David L.
AU - Jethra, Aashish I.
AU - Nash, Oyekanmi
AU - Adeyefa, Christopher A.O.
AU - Adu, Festus D.
AU - Swayne, David
AU - Basler, Christopher F.
PY - 2008/11
Y1 - 2008/11
N2 - Three highly pathogenic avian influenza subtype H5N1 and 4 Newcastle disease viruses were isolated from sick or dead chickens in southwestern Nigeria. Sequencing and phylogenetic analysis placed them within H5N1 subclade 2.2.2. Intravenous and intranasal pathogenicity tests produced systemic disease with vascular endothelial cell tropism in chickens.
AB - Three highly pathogenic avian influenza subtype H5N1 and 4 Newcastle disease viruses were isolated from sick or dead chickens in southwestern Nigeria. Sequencing and phylogenetic analysis placed them within H5N1 subclade 2.2.2. Intravenous and intranasal pathogenicity tests produced systemic disease with vascular endothelial cell tropism in chickens.
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UR - http://www.scopus.com/inward/citedby.url?scp=55549121960&partnerID=8YFLogxK
U2 - 10.3201/eid1411.080557
DO - 10.3201/eid1411.080557
M3 - Article
C2 - 18976562
AN - SCOPUS:55549121960
SN - 1080-6040
VL - 14
SP - 1753
EP - 1755
JO - Emerging infectious diseases
JF - Emerging infectious diseases
IS - 11
ER -