TY - JOUR
T1 - Peruvian horse sickness virus and Yunnan orbivirus, isolated from vertebrates and mosquitoes in Peru and Australia
AU - Attoui, Houssam
AU - Mendez-lopez, Maria Rosario
AU - Rao, Shujing
AU - Hurtado-Alendes, Ana
AU - Lizaraso-Caparo, Frank
AU - Jaafar, Fauziah Mohd
AU - Samuel, Alan R.
AU - Belhouchet, Mourad
AU - Pritchard, Lindsay I.
AU - Melville, Lorna
AU - Weir, Richard P.
AU - Hyatt, Alex D.
AU - Davis, Steven S.
AU - Lunt, Ross
AU - Calisher, Charles H.
AU - Tesh, Robert B.
AU - Fujita, Ricardo
AU - Mertens, Peter P.C.
N1 - Funding Information:
The authors wish to thank Mr. Roberto Fernandez from Navy Medical Research Center Detachment of USA in Lima for identification and the taxonomic classification of the arthropods collected in this study. Staff at IAH were supported by the EU Grant “Reo ID” number QLK2-2000-00143, by the EU coordination action MedReoNet (Contract N° 044285) and by funding from both Defra and the BBSRC.
PY - 2009/11/25
Y1 - 2009/11/25
N2 - During 1997, two new viruses were isolated from outbreaks of disease that occurred in horses, donkeys, cattle and sheep in Peru. Genome characterization showed that the virus isolated from horses (with neurological disorders, 78% fatality) belongs to a new species the Peruvian horse sickness virus (PHSV), within the genus Orbivirus, family Reoviridae. This represents the first isolation of PHSV, which was subsequently also isolated during 1999, from diseased horses in the Northern Territory of Australia (Elsey virus, ELSV). Serological and molecular studies showed that PHSV and ELSV are very similar in the serotype-determining protein (99%, same serotype). The second virus (Rioja virus, RIOV) was associated with neurological signs in donkeys, cattle, sheep and dogs and was shown to be a member of the species Yunnan orbivirus (YUOV). RIOV and YUOV are also almost identical (97% amino acid identity) in the serotype-determining protein. YUOV was originally isolated from mosquitoes in China.
AB - During 1997, two new viruses were isolated from outbreaks of disease that occurred in horses, donkeys, cattle and sheep in Peru. Genome characterization showed that the virus isolated from horses (with neurological disorders, 78% fatality) belongs to a new species the Peruvian horse sickness virus (PHSV), within the genus Orbivirus, family Reoviridae. This represents the first isolation of PHSV, which was subsequently also isolated during 1999, from diseased horses in the Northern Territory of Australia (Elsey virus, ELSV). Serological and molecular studies showed that PHSV and ELSV are very similar in the serotype-determining protein (99%, same serotype). The second virus (Rioja virus, RIOV) was associated with neurological signs in donkeys, cattle, sheep and dogs and was shown to be a member of the species Yunnan orbivirus (YUOV). RIOV and YUOV are also almost identical (97% amino acid identity) in the serotype-determining protein. YUOV was originally isolated from mosquitoes in China.
KW - Australia
KW - China
KW - Emerging viruses
KW - Neurological signs
KW - Orbivirus
KW - Peru
KW - Peruvian horse sickness
KW - Reoviridae
KW - Yunnan orbivirus
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U2 - 10.1016/j.virol.2009.08.032
DO - 10.1016/j.virol.2009.08.032
M3 - Article
C2 - 19766284
AN - SCOPUS:70449127076
SN - 0042-6822
VL - 394
SP - 298
EP - 310
JO - Virology
JF - Virology
IS - 2
ER -