TY - JOUR
T1 - Permeability of Normal and Cataractous Rabbit Lenses to Glutathione
AU - Srivastava, Satish K.
AU - Beutler, Ernest
N1 - Funding Information:
This study was supported by PHS Grant HD-01974 and NIH General Research Support Grant FR-05471.
PY - 1968/2
Y1 - 1968/2
N2 - Rabbit lenses were made cataractous by incubating in culture medium with added tyrosine and tyrosinase. The content of GSH was drastically lowered in the cataractous lens. The GSH which was lost from the lens could be partially recovered as GSSG in the medium. This finding may explain the fate of lens GSH, both normally and in cataract formation.
AB - Rabbit lenses were made cataractous by incubating in culture medium with added tyrosine and tyrosinase. The content of GSH was drastically lowered in the cataractous lens. The GSH which was lost from the lens could be partially recovered as GSSG in the medium. This finding may explain the fate of lens GSH, both normally and in cataract formation.
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U2 - 10.3181/00379727-127-32727
DO - 10.3181/00379727-127-32727
M3 - Article
C2 - 5645039
AN - SCOPUS:0014249048
SN - 0037-9727
VL - 127
SP - 512
EP - 514
JO - Proceedings of the Society for Experimental Biology and Medicine
JF - Proceedings of the Society for Experimental Biology and Medicine
IS - 2
ER -